SCHEMBL650919

SCHEMBL650919

CCN(CC)C(C)c1ccccc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.59
GABRA1 P14867 2/20 0.54
GABRB2 P47870 2/20 0.54
POLB P06746 2/20 0.43
ADRA2A P08913 2/20 0.42
KCNH2 Q12809 2/20 0.42
PGR P06401 1/20 0.42
ADRA2B P18089 1/20 0.42
HTR2A P28223 1/20 0.42
HRH1 P35367 1/20 0.42
HSP90AA1 P07900 1/20 0.37
HSP90AB1 P08238 1/20 0.37
HPGD P15428 3/20 0.35
HIF1A Q16665 3/20 0.35
CA2 P00918 2/20 0.35
LMNA P02545 2/20 0.35
CYP3A4 P08684 2/20 0.35
BLM P54132 2/20 0.35
CYP1A2 P05177 2/20 0.35
SLC6A2 P23975 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10490575 0.83 TSHR (0.44) TSHRGABRA1GABRB2POLBADRA2A
SCHEMBL12995993 0.81 GABRA1 (0.60) TSHRGABRA1GABRB2POLBHTR2A
SCHEMBL10243317 0.79 TSHR (0.41) TSHRGABRA1GABRB2POLBADRA2A
SCHEMBL11304684 0.78 TSHR (0.47) TSHRGABRA1GABRB2POLBADRA2A
SCHEMBL5982527 0.78 ADRA2A (0.39) TSHRGABRA1GABRB2ADRA2AKCNH2
SCHEMBL29439345 0.77 ADRA2A (0.40) TSHRGABRA1GABRB2ADRA2AKCNH2
SCHEMBL36796 0.77 GABRA1 (0.60) TSHRGABRA1GABRB2POLBKCNH2
SCHEMBL473376 0.76 ALDH1A1 (0.39) TSHRADRA2AKCNH2PGRADRA2B
SCHEMBL2268932 0.76 KCNH2 (0.38) TSHRGABRA1GABRB2ADRA2AKCNH2
SCHEMBL5983435 0.76 TSHR (0.48) TSHRGABRA1GABRB2POLBADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11931711-B2 Microcapsule clusters ENCAPSYS, LLC (US) 2024-03-19 US disclosed
US-20230264161-A1 Microcapsule Clusters ENCAPSYS LLC (US) 2023-08-24 US disclosed
EP-3946710-A1 MICROCAPSULE CLUSTERS Encapsys, LLC (US) 2022-02-09 EP disclosed
EP-3206782-B1 CONTROLLED RELEASE DUAL WALLED MICROCAPSULES PROCTER & GAMBLE (US) 2021-12-15 EP disclosed
US-11180714-B2 Controlled release microcapsules ENCAPSYS, LLC (US) 2021-11-23 US disclosed
US-20200316551-A1 Microcapsule Clusters ENCAPSYS, LLC 2020-10-08 US disclosed
US-20190345410-A1 CONTROLLED RELEASE MICROCAPSULES ENCAPSYS, LLC (US) 2019-11-14 US disclosed
US-10456766-B2 Controlled release dual walled microcapsules ENCAPSYS LLC (US) 2019-10-29 US disclosed
US-10428294-B2 Controlled release microcapsules ENCAPSYS, LLC (US) 2019-10-01 US disclosed
US-20190282989-A1 CONTROLLED RELEASE DUAL WALLED MICROCAPSULES ENCAPSYS LLC (US) 2019-09-19 US disclosed
US-4699931-A REACTING POLYISOCYANATE WITH POLYEPOXIDE-THERMAL STABILITY OLIN CORPORATION (US) 1987-10-13 US disclosed
EP-0028331-B2 Process for preparing urethanes BAYER AG (DE) 1987-05-20 EP disclosed
EP-0027940-B2 PROCESS FOR PREPARING URETHANES BAYER AG (DE) 1986-12-30 EP disclosed
EP-0087047-B1 PROCESS FOR THE PREPARATION OF N SUBSTITUTED URETHANES BAYER AG (DE) 1985-08-07 EP disclosed
EP-0027940-B1 PROCESS FOR PREPARING URETHANES BAYER AG (DE) 1983-09-14 EP disclosed
EP-0087047-A2 Process for the preparation of N substituted urethanes BAYER AG (DE) 1983-08-31 EP disclosed
US-4388238-A FROM PRIMARY AMINES, ALCOHOLS, AND CARBONYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1983-06-14 US disclosed
EP-0028331-B1 Process for preparing urethanes BAYER AG (DE) 1982-12-15 EP disclosed
US-4126741-A High-modulus polyisocyanurate elastomers THE UPJOHN COMPANY (US) 1978-11-21 US disclosed
US-4126742-A High-modulus polyisocyanurate elastomers THE UPJOHN COMPANY (US) 1978-11-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190345410-A1 CONTROLLED RELEASE MICROCAPSULES NSF, CRH, CHMP4B TSHR 2714/4885GABRA1 2358/4885GABRB2 3348/4885
US-10456766-B2 Controlled release dual walled microcapsules MYADM, MCHR2, MCHR1 TSHR 1759/4885GABRA1 3612/4885GABRB2 3883/4885
US-10428294-B2 Controlled release microcapsules NSF, CRH, CHMP4B TSHR 2714/4885GABRA1 2358/4885GABRB2 3348/4885
US-20190282989-A1 CONTROLLED RELEASE DUAL WALLED MICROCAPSULES MYADM, MCHR2, MCHR1 TSHR 1759/4885GABRA1 3612/4885GABRB2 3883/4885
US-11180714-B2 Controlled release microcapsules NSF, CRH, CHMP4B TSHR 2714/4885GABRA1 2358/4885GABRB2 3348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.