SCHEMBL6532417

SCHEMBL6532417

CCCCc1ccc(CN(CCC(=O)O)Cc2cc(C)ccc2C)cc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
FFAR1 O14842 1/20 0.42
PLK1 P53350 2/20 0.41
PPARA Q07869 1/20 0.41
S1PR1 P21453 3/20 0.41
CNR2 P34972 1/20 0.41
S1PR3 Q99500 2/20 0.41
S1PR2 O95136 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41
TRPM2 O94759 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6510333 0.96 PLK1 (0.46) ALDH1A1PLK1S1PR1S1PR3S1PR2
SCHEMBL6511970 0.91 ALDH1A1 (0.42) ALDH1A1HPGDHSD17B10PLK1S1PR1
SCHEMBL6509333 0.91 FFAR1 (0.46) ALDH1A1HPGDHSD17B10FFAR1PLK1
SCHEMBL6509250 0.90 CSF1R (0.39) PPARACYP3A4CYP2D6CYP2C9FFAR4
SCHEMBL6515022 0.87 PLK1 (0.44) ALDH1A1PLK1S1PR1S1PR3S1PR2
SCHEMBL6511174 0.81 FFAR1 (0.43) FFAR1PPARAS1PR1FFAR4
SCHEMBL6510860 0.81 RAB9A (0.41) FFAR1PPARAFFAR4
SCHEMBL6512710 0.80 ALDH1A1 (0.43) ALDH1A1HPGDHSD17B10S1PR1S1PR3
SCHEMBL6511703 0.80 NPC1 (0.40) FFAR1PPARAFFAR4
SCHEMBL6509314 0.79 MEP1B (0.46) HPGDFFAR1PPARACYP2D6FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005097100-A2 ANTIBACTERIAL AGENTS PROLYSIS LTD. (GB) 2005-10-20 WO disclosed