Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 8/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 2/20 | 0.43 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511970 | 0.97 | ALDH1A1 (0.42) | PLK1S1PR1S1PR3S1PR2THRA | |
| SCHEMBL6510333 | 0.91 | PLK1 (0.46) | PLK1S1PR1S1PR3S1PR2THRA | |
| SCHEMBL6510672 | 0.90 | RAB9A (0.42) | PLK1S1PR1 | |
| SCHEMBL6531857 | 0.89 | PPARA (0.42) | PLK1S1PR1S1PR3S1PR2THRA | |
| SCHEMBL6532417 | 0.87 | ALDH1A1 (0.43) | PLK1S1PR1S1PR3S1PR2THRA | |
| SCHEMBL6510860 | 0.87 | RAB9A (0.41) | — | |
| SCHEMBL6509333 | 0.85 | FFAR1 (0.46) | PLK1S1PR1S1PR3S1PR2THRA | |
| SCHEMBL6527447 | 0.81 | S1PR1 (0.43) | S1PR1S1PR3S1PR2THRATHRB | |
| SCHEMBL6515073 | 0.80 | PLA2G4B (0.47) | THRATHRB | |
| SCHEMBL6511699 | 0.80 | FFAR1 (0.43) | PLK1S1PR1THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |