Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 2/20 | 0.43 |
| ▸ | PDE6D | O43924 | 1/20 | 0.43 |
| ▸ | PDE6A | P16499 | 1/20 | 0.43 |
| ▸ | PDE6G | P18545 | 1/20 | 0.43 |
| ▸ | PDE6B | P35913 | 1/20 | 0.43 |
| ▸ | PDE6C | P51160 | 1/20 | 0.43 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532623 | 0.82 | NPC1 (0.47) | CNR1ALDH1A1HPGDHTTLMNA | |
| SCHEMBL6509465 | 0.77 | GABRA2 (0.44) | CNR1 | |
| SCHEMBL6532620 | 0.77 | CNR1 (0.47) | CNR1 | |
| SCHEMBL6510594 | 0.75 | CNR1 (0.74) | CNR1 | |
| SCHEMBL4800431 | 0.72 | PTGS2 (0.54) | NR1H2NR1H3ALDH1A1HPGDTDP1 | |
| SCHEMBL6507095 | 0.70 | CNR1 (0.53) | CNR1ALDH1A1HPGDTDP1NPBWR1 | |
| SCHEMBL4394435 | 0.70 | PTGS2 (0.54) | NR1H2NR1H3ALDH1A1HPGDNPBWR1 | |
| SCHEMBL4047786 | 0.69 | PTGS2 (0.70) | NR1H2NR1H3ALDH1A1NPBWR1HTT | |
| SCHEMBL6514552 | 0.67 | CNR1 (0.63) | CNR1LMNANPSR1 | |
| SCHEMBL25341629 | 0.66 | NPBWR1 (0.60) | ALDH1A1HPGDRECQLTDP1NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | claimed |
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |