Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTGIR | P43119 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513021 | 0.88 | PDE10A (0.35) | L3MBTL1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL6527853 | 0.86 | HTR3E (0.34) | L3MBTL1SMN1; SMN2POLBBRAF | |
| SCHEMBL6513229 | 0.85 | ALDH1A1 (0.35) | L3MBTL1SMN1; SMN2LMNAPOLBHPGD | |
| SCHEMBL6513922 | 0.83 | TDP1 (0.38) | SMN1; SMN2LMNAMEN1KMT2AHPGD | |
| SCHEMBL6508234 | 0.80 | HPGD (0.37) | L3MBTL1RXFP1SMN1; SMN2AURKBPOLB | |
| SCHEMBL6510073 | 0.80 | HPGD (0.39) | L3MBTL1RXFP1SMN1; SMN2AURKBPOLB | |
| SCHEMBL6510069 | 0.80 | HPGD (0.39) | L3MBTL1RXFP1SMN1; SMN2AURKBPOLB | |
| SCHEMBL6528749 | 0.79 | MEN1 (0.37) | L3MBTL1AURKBPOLBMEN1KMT2A | |
| SCHEMBL6528181 | 0.79 | TBK1 (0.35) | L3MBTL1AURKBPOLBMEN1KMT2A | |
| SCHEMBL6514102 | 0.79 | HPGD (0.40) | L3MBTL1RXFP1SMN1; SMN2AURKBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003103-A2 | 2, 4, 6-TRI-SUBSTITUTED 6-MEMBERED HETEROCYCLES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | ASTRAZENECA AB (SE) | 2005-01-13 | — | — | WO | claimed |
| WO-2005003103-A2 | 2, 4, 6-TRI-SUBSTITUTED 6-MEMBERED HETEROCYCLES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | ASTRAZENECA AB (SE) | 2005-01-13 | — | — | WO | disclosed |