Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6514948 | 0.83 | — | — | |
| SCHEMBL6514992 | 0.82 | CA2 (0.31) | CA2CA4 | |
| SCHEMBL6281180 | 0.76 | RXRA (0.34) | — | |
| SCHEMBL6280426 | 0.74 | FDPS (0.33) | MEN1KMT2A | |
| SCHEMBL6280922 | 0.71 | GGPS1 (0.32) | — | |
| SCHEMBL6519361 | 0.69 | — | — | |
| SCHEMBL6793260 | 0.68 | ALOX5 (0.44) | MEN1KMT2A | |
| SCHEMBL34461212 | 0.68 | KDM1A (0.39) | — | |
| SCHEMBL6507886 | 0.67 | RXRA (0.40) | — | |
| SCHEMBL34461137 | 0.65 | KDM1A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042509-A1 | 7-`(7-ALKOXY)-CHROM-3-EN-6-YL!-HEPTATRIENOIC ACID AND 7-`(3ALKOXY)-5,6-DIHYDRONAPHTHALEN-2-YL!-HEPTATRIENOIC ACID DERIVATIVES MODULATORS | ALLERGAN, INC. (US) | 2005-05-12 | — | — | WO | disclosed |