Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.31 |
| ▸ | PGR | P06401 | 3/20 | 0.31 |
| ▸ | AR | P10275 | 3/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | POLA1 | P09884 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510187 | 0.82 | CA1 (0.30) | CA2CA4 | |
| SCHEMBL6281180 | 0.76 | RXRA (0.34) | — | |
| SCHEMBL6280426 | 0.76 | FDPS (0.33) | — | |
| SCHEMBL6280922 | 0.71 | GGPS1 (0.32) | — | |
| SCHEMBL34461212 | 0.68 | KDM1A (0.39) | NR3C1PGRARNR3C2 | |
| SCHEMBL6793260 | 0.68 | ALOX5 (0.44) | — | |
| SCHEMBL6514948 | 0.67 | — | — | |
| SCHEMBL34461137 | 0.65 | KDM1A (0.35) | NR3C1PGRARNR3C2 | |
| SCHEMBL9952087 | 0.64 | IMPDH2 (0.38) | CA2CA4 | |
| SCHEMBL34461266 | 0.63 | AKT1 (0.37) | NR3C1PGRARNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042509-A1 | 7-`(7-ALKOXY)-CHROM-3-EN-6-YL!-HEPTATRIENOIC ACID AND 7-`(3ALKOXY)-5,6-DIHYDRONAPHTHALEN-2-YL!-HEPTATRIENOIC ACID DERIVATIVES MODULATORS | ALLERGAN, INC. (US) | 2005-05-12 | — | — | WO | disclosed |