SCHEMBL6510247

SCHEMBL6510247

C#Cc1cc(CC)c(C#C)cc1CC

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12959691 0.82 PDE3B (0.35) PGK1ALDH1A1MAPTHTT
SCHEMBL12959692 0.77 L3MBTL1 (0.40) ALDH1A1MAPTHTT
SCHEMBL17530142 0.77 MAPT (0.36) ALDH1A1MAPTHTT
SCHEMBL11661685 0.77 TRPA1 (0.39) ALDH1A1MAPT
SCHEMBL9267363 0.76 RXRA (0.43)
SCHEMBL13185296 0.75 MAPT (0.34) ALDH1A1MAPTHTT
SCHEMBL8293813 0.75 KEAP1 (0.35) PGK1KEAP1NFE2L2
SCHEMBL458042 0.74
SCHEMBL15063862 0.74
SCHEMBL17679934 0.73 CYP2A6 (0.44) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050101063-A1 Three-terminal field-controlled molecular devices TOUR JAMES M (US) 2005-05-12 US disclosed
WO-2002035580-A2 THREE-TERMINAL FIELD-CONTROLLED MOLECULAR DEVICES MOLECULAR ELECTRONICS CORPORATION (US) 2002-05-02 WO disclosed