Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.51 |
| ▸ | F3 | P13726 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21333606 | 0.83 | PARP10 (0.53) | PARP1PARP10ALDH1A1KMT2APARP11 | |
| SCHEMBL2060799 | 0.81 | NR1H2 (0.41) | PARP1PARP10KDM4EALDH1A1KMT2A | |
| SCHEMBL16349626 | 0.77 | PARP1 (0.46) | PARP1PARP10HTR2CHTR2AHTR2B | |
| SCHEMBL2060905 | 0.77 | CASP3 (0.50) | OPRK1LMNAALDH1A1KMT2AGAA | |
| SCHEMBL69760 | 0.76 | OPRK1 (0.48) | HTR2COPRK1NR1I2ADORA3ADRA1A | |
| Hydrochloric Acid SCHEMBL30123734 | 0.76 | PARP1 (0.44) | PARP1PARP10HTR2CHTR2AHTR2B | |
| SCHEMBL23160030 | 0.75 | PARP10 (0.51) | PARP1PARP10ALDH1A1KMT2AGAA | |
| SCHEMBL30914657 | 0.75 | PARP10 (0.51) | PARP1PARP10ALDH1A1KMT2AGAA | |
| SCHEMBL607738 | 0.75 | LMNA (0.51) | PARP1PARP10F7F3HTR2C | |
| SCHEMBL30285468 | 0.74 | PRMT5 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12496297-B1 | Compositions of autophagy modulating agents and uses thereof | WASHINGTON UNIVERSITY (US) | 2025-12-16 | — | — | US | disclosed |
| US-20050203898-A1 | System and method for the indexing of organic chemical structures mined from text documents | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12496297-B1 | Compositions of autophagy modulating agents and uses thereof | BECN1, TFEB, ATG7 | PARP1 1082/4885PARP10 1857/4885F7 4787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.