Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511048 | 0.80 | ALDH1A1 (0.45) | TSHRSMN1; SMN2GRM8GRM4KDM4E | |
| SCHEMBL3069248 | 0.75 | CNR2 (0.37) | TSHRLMNAALDH1A1 | |
| SCHEMBL5160712 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2GRM8GRM4KDM4ETBXAS1 | |
| SCHEMBL5929551 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2GRM8GRM4KDM4ETBXAS1 | |
| SCHEMBL9159608 | 0.70 | CYP2C19 (0.46) | SMN1; SMN2GRM8GRM4KDM4ETBXAS1 | |
| SCHEMBL21240743 | 0.69 | HTR7 (0.42) | SMN1; SMN2PTGFRGAAMGAMSI | |
| SCHEMBL503349 | 0.69 | HTR7 (0.42) | SMN1; SMN2PTGFRGAAMGAMSI | |
| SCHEMBL6505819 | 0.65 | SMN1; SMN2 (0.58) | SMN1; SMN2GRM8GRM4KDM4ETBXAS1 | |
| SCHEMBL2450934 | 0.65 | SMN1; SMN2 (0.53) | SMN1; SMN2GRM8GRM4KDM4ETBXAS1 | |
| SCHEMBL21853748 | 0.65 | SMN1; SMN2 (0.53) | SMN1; SMN2GRM8GRM4KDM4ETBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123727-A1 | 3-ARYL-3-HYDROXY- AND 3-ARYL-3-OXOPROPIONIC ACID ESTERS AS FUNGICIDES | CROPSOLUTION, INC. (US) | 2005-12-29 | — | — | WO | disclosed |