Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508460 | 0.86 | HTR2C (0.36) | LTB4RMEP1BHDAC3HDAC1HDAC2 | |
| SCHEMBL6511525 | 0.85 | LTB4R (0.40) | LTB4RMEP1BFFAR1BCHE | |
| SCHEMBL6511901 | 0.85 | TSHR (0.49) | FFAR1TSHR | |
| SCHEMBL6512357 | 0.85 | TAS2R14 (0.43) | MTNR1AMTNR1BLTA4HMEP1BHDAC3 | |
| SCHEMBL6511823 | 0.85 | LTB4R (0.40) | LTB4RMTNR1AMTNR1BLTA4HMEP1B | |
| SCHEMBL6509240 | 0.84 | PPARA (0.41) | LTB4RFFAR1 | |
| SCHEMBL6511514 | 0.84 | OPRM1 (0.37) | LTB4RMEP1BFFAR1MEN1MAPT | |
| SCHEMBL6512519 | 0.84 | POLB (0.50) | LTB4RLTA4HHDAC3HDAC1HDAC2 | |
| SCHEMBL6511023 | 0.84 | HDAC3 (0.40) | LTB4RMTNR1AMTNR1BLTA4HMEP1B | |
| SCHEMBL6511657 | 0.84 | HDAC3 (0.50) | MTNR1AMTNR1BLTA4HMEP1BHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |