Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28362610 | 0.91 | NR1H4 (0.58) | NR1H4MAPTALDH1A1TSHRHSD17B10 | |
| SCHEMBL4800556 | 0.85 | CES2 (0.56) | TSHRPGRADRA2AADRA2BHTR2A | |
| SCHEMBL702447 | 0.83 | TDP1 (0.61) | TDP1L3MBTL1MAPTALDH1A1TSHR | |
| SCHEMBL10894082 | 0.83 | TDP1 (0.61) | TDP1L3MBTL1MAPTALDH1A1TSHR | |
| SCHEMBL6758776 | 0.83 | ALDH1A1 (0.68) | NR1H4TDP1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL7041252 | 0.81 | TDP1 (0.49) | NR1H4TDP1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL8021929 | 0.80 | PTGS2 (0.54) | TDP1L3MBTL1MAPTALDH1A1HSD17B10 | |
| SCHEMBL9541003 | 0.80 | LMNA (0.53) | TDP1L3MBTL1MAPTALDH1A1HSD17B10 | |
| SCHEMBL4806377 | 0.80 | PTGS2 (0.69) | TDP1L3MBTL1MAPTALDH1A1PGR | |
| SCHEMBL2926204 | 0.80 | CES2 (0.53) | TDP1L3MBTL1MAPTALDH1A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585216-B1 | PI-ALLYLPALLADIUM AND PI-ALLYLNICKEL COMPLEXES FOR USE AS CATALYSTS IN CARBON-CARBON AND CARBON-NITROGEN COUPLING REACTIONS | JOHNSON MATTHEY PLC (GB) | 2019-11-20 | — | — | EP | disclosed |
| US-20190016742-A1 | Complexes | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-01-17 | — | — | US | disclosed |
| US-10167305-B2 | Allyl complexes for use in coupling reactions | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-01-01 | — | — | US | disclosed |
| US-20130165660-A1 | COMPLEXES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2013-06-27 | — | — | US | disclosed |
| US-20130165660-A1 | COMPLEXES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2013-06-27 | — | — | US | disclosed |
| WO-2011161451-A1 | COMPLEXES | JOHNSON MATTHEY PLC (GB) | 2011-12-29 | — | — | WO | disclosed |
| US-6867310-B1 | Arylation and vinylation of activated carbons | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-03-15 | — | — | US | disclosed |
| WO-2004028252-A1 | PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING PEST | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2004-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167305-B2 | Allyl complexes for use in coupling reactions | AP3M1, AP1M1, C9 | NR1H4 1719/4885TDP1 4386/4885L3MBTL1 2606/4885 |
| US-20190016742-A1 | Complexes | C5, C1S, C9 | NR1H4 1776/4885TDP1 4171/4885L3MBTL1 3265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.