Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619456 | 0.83 | POLB (0.44) | POLBHCAR2KDM4EHTTALOX15 | |
| SCHEMBL6505188 | 0.79 | POLB (0.41) | POLBHCAR2KDM4EHTTALOX15 | |
| SCHEMBL1522910 | 0.77 | CYP1A2 (0.39) | POLBHCAR2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL334406 | 0.76 | POLB (0.52) | POLBHCAR2KDM4EHTTALOX15 | |
| SCHEMBL29598214 | 0.76 | POLB (0.52) | POLBHCAR2KDM4EHTTALOX15 | |
| SCHEMBL15301359 | 0.74 | PKM (0.47) | POLBHCAR2SMN1; SMN2PKM | |
| SCHEMBL3723569 | 0.73 | CHRNB2 (0.47) | POLBHCAR2KDM4EHTTSMN1; SMN2 | |
| Acetic Acid SCHEMBL28229691 | 0.73 | POLB (0.48) | POLBHCAR2KDM4EHTTALOX15 | |
| SCHEMBL1475664 | 0.73 | POLB (0.48) | POLBHCAR2KDM4EHTTALOX15 | |
| SCHEMBL1749636 | 0.72 | KMT2A (0.56) | POLBHTTALOX15SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | POLB 3/4885HCAR2 4661/4885KDM4E 4352/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | POLB 35/4885HCAR2 4586/4885KDM4E 4075/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | POLB 19/4885HCAR2 4497/4885KDM4E 3897/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | POLB 3/4885HCAR2 4661/4885KDM4E 4352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.