Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511663 | 0.90 | HTT (0.43) | KMT2AMEN1HTTSLC1A5PTPN1 | |
| SCHEMBL6510100 | 0.88 | FFAR1 (0.41) | HTTMEP1BSLC1A5PTPN1PTGER1 | |
| SCHEMBL6511657 | 0.85 | HDAC3 (0.50) | LMNAKMT2AMEN1HTTMEP1B | |
| SCHEMBL6510335 | 0.81 | HTT (0.43) | LMNAPKMKMT2AMEN1HTT | |
| SCHEMBL6515044 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1MEP1BPTPN1ALDH1A1 | |
| SCHEMBL6509679 | 0.81 | SMN1; SMN2 (0.45) | LMNAPKMKMT2AMEN1HTT | |
| SCHEMBL6511947 | 0.80 | MTNR1A (0.47) | LMNAKMT2AMEN1MEP1BPTPN1 | |
| SCHEMBL6508483 | 0.80 | TSHR (0.45) | KMT2AMEP1BALDH1A1SNCA | |
| SCHEMBL6511151 | 0.79 | RAB9A (0.43) | LMNAPKMHTTMEP1BSLC1A5 | |
| SCHEMBL6514104 | 0.79 | KMT2A (0.42) | LMNAPKMKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |