Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511947 | 0.91 | MTNR1A (0.47) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL6510153 | 0.90 | PKM (0.47) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL6512357 | 0.90 | TAS2R14 (0.43) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL6519103 | 0.90 | KMT2A (0.50) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL6531193 | 0.88 | LTA4H (0.46) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL6511878 | 0.87 | FFAR1 (0.49) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL6513388 | 0.87 | MEP1B (0.46) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL6511663 | 0.87 | HTT (0.43) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL6512251 | 0.87 | FAAH (0.41) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL6515044 | 0.87 | ALDH1A1 (0.41) | HDAC3HDAC1HDAC2HDAC8NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |