SCHEMBL6515044

SCHEMBL6515044

Cc1ccccc1CN(CCC(=O)O)Cc1cccc(Cc2ccccc2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
RORC P51449 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
LTA4H P09960 2/20 0.40
MAPT P10636 1/20 0.40
PTPN1 P18031 1/20 0.40
MEP1B Q16820 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
NCOR2 Q9Y618 1/20 0.39
FFAR1 O14842 1/20 0.39
TAS2R14 Q9NYV8 1/20 0.39
PTGER1 P34995 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6510202 0.90 NPC1 (0.41) ALDH1A1BCHEACHEMEN1KMT2A
SCHEMBL6511876 0.89 SLC1A5 (0.43) ALDH1A1MEN1KMT2AMAPTMEP1B
SCHEMBL6511657 0.87 HDAC3 (0.50) ALDH1A1MEN1KMT2AMTNR1AMTNR1B
SCHEMBL6512357 0.86 TAS2R14 (0.43) ALDH1A1MEN1KMT2AMTNR1AMTNR1B
SCHEMBL6511663 0.85 HTT (0.43) BCHEACHERORCMEN1KMT2A
SCHEMBL6509679 0.85 SMN1; SMN2 (0.45) ALDH1A1RORCMEN1KMT2APTPN1
SCHEMBL6511947 0.84 MTNR1A (0.47) ALDH1A1BCHEACHERORCMEN1
SCHEMBL6513642 0.84 ESR1 (0.49) BCHEACHEMEN1KMT2AMTNR1A
SCHEMBL6511151 0.83 RAB9A (0.43) ALDH1A1MTNR1AMTNR1BLTA4HPTPN1
SCHEMBL6510100 0.83 FFAR1 (0.41) MTNR1AMTNR1BLTA4HMAPTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005097100-A2 ANTIBACTERIAL AGENTS PROLYSIS LTD. (GB) 2005-10-20 WO disclosed