Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 5/20 | 0.33 |
| ▸ | HTR1A | P08908 | 4/20 | 0.33 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29163642 | 0.79 | HTR1A (0.42) | LMNADRD2HTR1AHTR2ATSHR | |
| SCHEMBL10534322 | 0.77 | MBTD1 (0.39) | LMNASLC18A3 | |
| SCHEMBL29140942 | 0.73 | NOTUM (0.37) | LMNASLC18A3 | |
| SCHEMBL28240821 | 0.70 | NOTUM (0.39) | LMNATSHRMEN1KMT2A | |
| SCHEMBL29163640 | 0.70 | NOTUM (0.39) | DRD4MEN1KMT2A | |
| SCHEMBL28740969 | 0.69 | HTR3E (0.41) | LMNADRD2TSHRKMT2ASLC18A3 | |
| SCHEMBL28344652 | 0.68 | — | — | |
| SCHEMBL10424519 | 0.67 | HTR1A (0.59) | LMNADRD2HTR1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL9270711 | 0.67 | LMNA (0.55) | LMNA | |
| SCHEMBL10922111 | 0.66 | QDPR (0.40) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005077885-A1 | RUTHENIUM-CATALYZED HYDROAMINATION OF OLEFINS | YALE UNIVERSITY (US) | 2005-08-25 | — | — | WO | disclosed |