Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933037 | 1.00 | DPYD (0.59) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL190003 | 0.83 | DPYD (0.62) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL65892 | 0.83 | DPYD (0.62) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL15798473 | 0.83 | DPYD (0.62) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL190328 | 0.80 | DPYD (0.59) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL190329 | 0.80 | DPYD (0.59) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL190378 | 0.79 | DPYD (0.59) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL6374591 | 0.79 | DPYD (0.59) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL190377 | 0.79 | DPYD (0.59) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL6374582 | 0.79 | DPYD (0.59) | DPYDMAPTALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194174-B1 | EXTENDING THE LIFETIME OF ANTICOAGULANT OLIGODEOXYNUCLEOTIDE APTAMERS IN BLOOD | UNIV ALBERTA SIMON FRASER UNI (CA) | 2005-09-21 | — | — | EP | disclosed |
| US-6780850-B1 | INHIBITING DEGRADATION OF A NUCLEIC ACID IN THE BLOOD COMPRISING ATTACHING STREPTAVIDIN OR A VARIANT THEREOF THAT RETAINS BIOTIN BINDING ACTIVITY TO SAID NUCLEIC ACID | TRIUMF (CA) | 2004-08-24 | — | — | US | disclosed |
| EP-0649840-B1 | Bis(hydroxymethyl)cyclopropylmethyl pyrimidine derivatives, their preparation and their use as anti-viral agents | AJINOMOTO KK (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-5496824-A | ZOSTER VIRUS WITH PYRIMIDINEDIONE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0649840-A1 | Bis(hydroxymethyl)cyclopropylmethyl pyrimidine derivatives, their preparation and their use as anti-viral agents | Ajinomoto Co., Inc. (JP) | 1995-04-26 | — | — | EP | disclosed |
| US-4668778-A | Nucleoside 5'-alkyl- or alkenylphosphate | YAMASA SHOYU KABUSHIKI KAISHA (JP) | 1987-05-26 | — | — | US | disclosed |
| EP-0097376-B1 | NUCLEOSIDE 5'-ALKYL- OR ALKENYLPHOSPHATE | Yamasa Shoyu Kabushiki Kaisha (JP) | 1986-09-17 | — | — | EP | disclosed |
| EP-0097376-A1 | Nucleoside 5'-alkyl- or alkenylphosphate | Yamasa Shoyu Kabushiki Kaisha (JP) | 1984-01-04 | — | — | EP | disclosed |
| US-4424211-A | VIRICIDES | REGA INSTITUUT VZW (BE) | 1984-01-03 | — | — | US | disclosed |