SCHEMBL6515095

SCHEMBL6515095

O=C(O)CCN(Cc1ccc(Sc2ccccc2)cc1)Cc1cccc(F)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.45
TAS2R14 Q9NYV8 3/20 0.45
HTT P42858 1/20 0.44
PKM P14618 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MMP1 P03956 1/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP13 P45452 1/20 0.43
MEP1B Q16820 2/20 0.42
NR3C1 P04150 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
HDAC3 O15379 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC8 Q9BY41 2/20 0.41
NCOR2 Q9Y618 2/20 0.41
TP53 P04637 1/20 0.41
FOLH1 Q04609 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6511878 0.87 FFAR1 (0.49) FFAR1TAS2R14HTTPKMMEN1
SCHEMBL6512708 0.83 HTT (0.45) HTTPKMMEN1KMT2AMMP13
SCHEMBL6515353 0.83 NR3C1 (0.60) FFAR1TAS2R14MMP1MMP2MMP9
SCHEMBL6509513 0.82 SLC6A9 (0.41) FFAR1PKMMEN1KMT2AMEP1B
SCHEMBL6510153 0.82 PKM (0.47) FFAR1TAS2R14HTTPKMMEN1
SCHEMBL6510665 0.81 MEP1B (0.39) HTTKMT2AMEP1BL3MBTL1CA12
SCHEMBL6519131 0.79 NR3C1 (0.55) FFAR1PKMNR3C1
SCHEMBL6510768 0.79 ALDH1A1 (0.43) TAS2R14HTTMEN1KMT2AMEP1B
SCHEMBL6511856 0.78 MEP1B (0.45) FFAR1TAS2R14PKMMEN1KMT2A
SCHEMBL6509442 0.78 RAB9A (0.41) FFAR1HTTPKMMEP1BHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005097100-A2 ANTIBACTERIAL AGENTS PROLYSIS LTD. (GB) 2005-10-20 WO disclosed