SCHEMBL6512954

SCHEMBL6512954

COCCCC(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
TSHR P16473 4/20 0.41
EPHX2 P34913 1/20 0.38
STING1 Q86WV6 1/20 0.36
DGAT1 O75907 1/20 0.35
HDAC1 Q13547 2/20 0.34
HDAC2 Q92769 2/20 0.34
HDAC8 Q9BY41 2/20 0.34
HDAC6 Q9UBN7 2/20 0.34
HDAC3 O15379 1/20 0.34
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA14 Q9ULX7 1/20 0.33
DGKA P23743 1/20 0.33
RECQL P46063 1/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20210578 0.94 ALDH1A1 (0.52) ALDH1A1TSHREPHX2STING1DGAT1
SCHEMBL20210520 0.92 ALDH1A1 (0.55) ALDH1A1TSHREPHX2STING1DGAT1
SCHEMBL12430010 0.86 DGAT1 (0.38) ALDH1A1TSHREPHX2STING1DGAT1
SCHEMBL8381948 0.84 TSHR (0.39) ALDH1A1TSHREPHX2DGAT1CA12
SCHEMBL1639757 0.84 TSHR (0.50) TSHREPHX2STING1DGAT1HDAC1
SCHEMBL134923 0.84 EPHX2 (0.46) ALDH1A1TSHREPHX2STING1DGAT1
SCHEMBL1863566 0.83 EPHX2 (0.38) TSHREPHX2STING1DGAT1HDAC1
SCHEMBL16656154 0.83 EPHX2 (0.38) TSHREPHX2STING1DGAT1HDAC1
SCHEMBL13344728 0.82 ALDH1A1 (0.39) ALDH1A1TSHRDGKARECQLMEN1
SCHEMBL2380206 0.81 EPHX2 (0.49) ALDH1A1TSHREPHX2HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3683243-B1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION HANWHA TOTALENERGIES PETROCHEMICAL CO LTD (KR) 2024-01-24 EP claimed
CN-108148153-B Solid catalyst and method for preparing propylene polymer or copolymer using the same 韩华道达尔有限公司 2021-08-10 CN claimed
EP-3683243-A1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION Hanwha Total Petrochemical Co., Ltd. (KR) 2020-07-22 EP claimed
EP-3683243-B1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION HANWHA TOTALENERGIES PETROCHEMICAL CO LTD (KR) 2024-01-24 EP disclosed
CN-116547287-A Inhibitors of APOL1 and methods of use thereof 弗特克斯药品有限公司 2023-08-04 CN disclosed
CN-108148153-B Solid catalyst and method for preparing propylene polymer or copolymer using the same 韩华道达尔有限公司 2021-08-10 CN disclosed
US-10808048-B2 Process of manufacture of catalyst and propylene polymer that use this or copolymer for propylene polymerization HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2020-10-20 US disclosed
EP-3683243-A1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION Hanwha Total Petrochemical Co., Ltd. (KR) 2020-07-22 EP disclosed
US-20180155461-A1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2018-06-07 US disclosed
US-20180155350-A1 CELL IMPERMEABLE COELENTERAZINE ANALOGUES JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2018-06-07 US disclosed
EP-3330299-A1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION Hanwha Total Petrochemical Co., Ltd. (KR) 2018-06-06 EP disclosed
WO-2017027645-A1 CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS MERCK SHARP & DOHME CORP. (US) 2017-02-16 WO disclosed
WO-2017027646-A1 CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS MERCK SHARP & DOHME CORP. (US) 2017-02-16 WO disclosed
US-20170044206-A1 CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS MERCK SHARP & DOHME CORP. (US) 2017-02-16 US disclosed
US-9180111-B2 Reduction in complement activation and inflammation during tissue injury by carotenoids, carotenoid analogs, or derivatives thereof CARDAX PHARMA, INC. (US) 2015-11-10 US disclosed
US-7691901-B2 Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation CARDAX PHARMACEUTICALS INC. (US) 2010-04-06 US disclosed
WO-2007031803-A2 MOLECULAR RESISTS BASED ON FUNCTIONALIZED POLYCARBOCYCLES NATIONAL CENTER FOR SCIENTIFIC RESEARCH (NCSR) ''DEMOKRITOS'' (GR) 2007-03-22 WO disclosed
WO-2005123702-A1 NEUTRAL ENDOPEPTIDASE INHIBITOR POLYMORPH PFIZER LIMITED (GB) 2005-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044206-A1 CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS STING1, CGAS, IFNAR1 ALDH1A1 4183/4885TSHR 2078/4885EPHX2 2856/4885
US-20180155350-A1 CELL IMPERMEABLE COELENTERAZINE ANALOGUES SI, GLB1, MRPL21 ALDH1A1 3715/4885TSHR 4172/4885EPHX2 2485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.