Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16702637 | 0.85 | CYP1A2 (0.38) | HSD17B10ALDH1A1ATMMAPK1NPSR1 | |
| SCHEMBL5754263 | 0.76 | ALDH1A1 (0.55) | HSD17B10ALDH1A1MAPK1NPSR1TDO2 | |
| SCHEMBL22258410 | 0.75 | ALDH1A1 (0.48) | HSD17B10ALDH1A1ATMMAPK1TDO2 | |
| SCHEMBL28443919 | 0.73 | MASP2 (0.42) | ALDH1A1MAPTTDP1LMNAHTT | |
| SCHEMBL29172201 | 0.73 | ATM (0.41) | HSD17B10ALDH1A1ATMMAPK1NPSR1 | |
| SCHEMBL25014 | 0.73 | HSD17B10 (0.50) | HSD17B10ALDH1A1MAPK1NPSR1TDO2 | |
| SCHEMBL29546125 | 0.73 | HSD17B10 (0.50) | HSD17B10ALDH1A1MAPK1NPSR1TDO2 | |
| SCHEMBL25135346 | 0.72 | MAPT (0.52) | HSD17B10ALDH1A1MAPK1NPSR1TDO2 | |
| SCHEMBL28153334 | 0.72 | MAOA (0.48) | HSD17B10ALDH1A1ATMMAPK1NPSR1 | |
| SCHEMBL5331238 | 0.72 | ATM (0.63) | HSD17B10ALDH1A1ATMMAPK1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050214471-A1 | Molecular templating of a surface | NOTTINGHAM, THE UNIVERSITY OF (GB) | 2005-09-29 | — | — | US | claimed |