Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | EBP | Q15125 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6515011 | 0.80 | HDAC1 (0.52) | ACKR3FAAHMAOBHTTCYP2D6 | |
| SCHEMBL6507970 | 0.73 | HDAC1 (0.52) | BCHEACHEACKR3KDM4EMAOB | |
| SCHEMBL6511431 | 0.71 | HDAC1 (0.46) | BCHEACHEACKR3MAPTFAAH | |
| SCHEMBL6509962 | 0.70 | HDAC1 (0.65) | ACKR3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6514449 | 0.70 | ESR1 (0.41) | BCHEACHEESR1MAPTRAB9A | |
| SCHEMBL6533816 | 0.67 | RAB9A (0.41) | MAPTFAAHRAB9AKDM4EHDAC3 | |
| SCHEMBL656907 | 0.66 | KDM4E (0.71) | MAPTFAAHRAB9AKDM4ENPSR1 | |
| SCHEMBL5903698 | 0.65 | HDAC1 (0.70) | MAPTFAAHRAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL1405290 | 0.65 | CYP2D6 (0.74) | BCHEACHEESR1MAPTKMT2A | |
| SCHEMBL12610941 | 0.65 | CYP2D6 (0.74) | BCHEACHEESR1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014588-A1 | SUBSTITUTED THIENYL-HYDROXAMIC ACIDS HAVING HISTONE DEACETYLASE ACTIVITY | ARGENTA DISCOVERY LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |