Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 3/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507755 | 0.91 | MAPK1 (0.38) | ALDH1A1HPGDL3MBTL1ATMMEN1 | |
| SCHEMBL6512244 | 0.90 | ALDH1A1 (0.42) | ALDH1A1MEP1BTHRB | |
| SCHEMBL6532562 | 0.89 | THRB (0.38) | ALDH1A1HPGDL3MBTL1ATMFFAR4 | |
| SCHEMBL6533747 | 0.89 | ATM (0.36) | ALDH1A1HPGDL3MBTL1ATMMEN1 | |
| SCHEMBL6533434 | 0.83 | BCL2L1 (0.37) | ALDH1A1ATMKDM4EMEN1KMT2A | |
| SCHEMBL6508452 | 0.82 | NPC1 (0.44) | CTSBFFAR4THRB | |
| SCHEMBL6510768 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HPGDL3MBTL1FFAR4LMNA | |
| SCHEMBL6509334 | 0.81 | PPARA (0.46) | FFAR4THRB | |
| SCHEMBL6516580 | 0.81 | CYP2D6 (0.50) | HPGDKDM4EMAPK1MEP1B | |
| SCHEMBL6510841 | 0.81 | PPARA (0.48) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |