SCHEMBL6512244

SCHEMBL6512244

CCCCSc1cccc(CN(CCC(=O)O)Cc2cccc(CC)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
MAPT P10636 1/20 0.38
MEP1B Q16820 2/20 0.37
PLA2G2A P14555 1/20 0.37
THRB P10828 2/20 0.36
HDAC3 O15379 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
NCOR2 Q9Y618 2/20 0.36
BCL2L1 Q07817 1/20 0.36
BAK1 Q16611 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36
THRA P10827 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6515019 0.90 ALDH1A1 (0.44) ALDH1A1MEP1BTHRB
SCHEMBL6507755 0.85 MAPK1 (0.38) ALDH1A1MAPTMEP1BTHRBNPSR1
SCHEMBL6533747 0.84 ATM (0.36) ALDH1A1MAPTTHRBNPSR1
SCHEMBL6532562 0.84 THRB (0.38) ALDH1A1MAPTTHRBBCL2L1BAK1
SCHEMBL6509203 0.82 PPARA (0.48) THRBTHRA
SCHEMBL6533434 0.82 BCL2L1 (0.37) ALDH1A1MAPTMEP1BPLA2G2ATHRB
SCHEMBL6511947 0.78 MTNR1A (0.47) ALDH1A1MAPTMEP1BHDAC3HDAC1
SCHEMBL6508452 0.74 NPC1 (0.44) THRBHDAC3HDAC1HDAC2HDAC8
SCHEMBL6509334 0.73 PPARA (0.46) THRBTHRA
SCHEMBL6510841 0.72 PPARA (0.48) THRBHDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005097100-A2 ANTIBACTERIAL AGENTS PROLYSIS LTD. (GB) 2005-10-20 WO disclosed