Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511151 | 0.91 | RAB9A (0.43) | RAB9AMEP1BMTNR1AMTNR1BLTA4H | |
| SCHEMBL6510100 | 0.91 | FFAR1 (0.41) | NPC1RAB9AMEP1BMTNR1AMTNR1B | |
| SCHEMBL6515044 | 0.90 | ALDH1A1 (0.41) | MEP1BMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL6512357 | 0.89 | TAS2R14 (0.43) | NPC1RAB9AMEP1BMTNR1AMTNR1B | |
| SCHEMBL6511876 | 0.87 | SLC1A5 (0.43) | NPC1RAB9AMEP1BMEN1KMT2A | |
| SCHEMBL6512683 | 0.86 | MEP1B (0.46) | NPC1RAB9AMEP1BLTA4HL3MBTL1 | |
| SCHEMBL6509250 | 0.85 | CSF1R (0.39) | NPC1RAB9APTGER1PTGER4PTGER3 | |
| SCHEMBL6518329 | 0.85 | NPC1 (0.39) | NPC1RAB9AMEP1BMEN1KMT2A | |
| SCHEMBL6511657 | 0.85 | HDAC3 (0.50) | MEP1BMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL6515089 | 0.84 | POLB (0.42) | MEP1BMEN1KMT2AMAPTSLC1A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |