Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15974260 | 1.00 | GAA (0.49) | GAAADAMTS5ADAMTS4ALDH1A1L3MBTL1 | |
| SCHEMBL25367549 | 0.84 | IDO1 (0.48) | GAAALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL28607425 | 0.83 | CXCR4 (0.46) | GAAADAMTS5ADAMTS4ALDH1A1L3MBTL1 | |
| SCHEMBL2340212 | 0.81 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1POLBSMN1; SMN2KDM4E | |
| SCHEMBL14357764 | 0.81 | HDAC8 (0.57) | GAAADAMTS5ADAMTS4POLBHDAC8 | |
| SCHEMBL1011632 | 0.81 | HDAC8 (0.57) | GAAADAMTS5ADAMTS4POLBHDAC8 | |
| SCHEMBL1011756 | 0.76 | BCHE (0.50) | GAAADAMTS5ADAMTS4ALDH1A1LMNA | |
| SCHEMBL11463218 | 0.75 | GAA (0.46) | GAAADAMTS5ADAMTS4ALDH1A1SMN1; SMN2 | |
| Phosphoric Acid SCHEMBL30514837 | 0.75 | ALDH1A1 (0.43) | ALDH1A1POLBLMNASMN1; SMN2HTT | |
| SCHEMBL5557748 | 0.75 | HDAC8 (0.43) | ALDH1A1LMNASMN1; SMN2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2276586-A | — | — | None | — | — | JP | disclosed |
| JP-6343483-A | — | — | None | — | — | JP | disclosed |
| JP-1045354-A | — | — | None | — | — | JP | disclosed |
| JP-1045336-A | — | — | None | — | — | JP | disclosed |
| JP-1320991-A | — | — | None | — | — | JP | disclosed |
| JP-2119796-A | — | — | None | — | — | JP | disclosed |
| JP-63273498-A | — | — | None | — | — | JP | disclosed |
| US-11028052-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2021-06-08 | — | — | US | disclosed |
| EP-3461816-B1 | FIVE-MEMBERED HETEROCYLIC COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-03-24 | — | — | EP | disclosed |
| US-10421727-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2019-09-24 | — | — | US | disclosed |
| WO-2002074752-A1 | METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2002-09-26 | — | — | WO | disclosed |
| US-5552317-A | POLYMERIZATION OF MONOMERS IN THE PRESENCE OF ENZYME AND HYDROLYSIS | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1996-09-03 | — | — | US | disclosed |
| US-5552318-A | ENANTIOSELECTIVE SYNTHESIS OF D-AMINO ACIDS | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1996-09-03 | — | — | US | disclosed |
| JP-H06343483-A | PRODUCTION OF L-HOMOPHENYLALANINE | AJINOMOTO CO INC | 1994-12-20 | — | — | JP | disclosed |
| JP-H02276586-A | PRODUCTION OF D-HOMOPHENYLALANINE | BIO-LE KK | 1990-11-13 | — | — | JP | disclosed |
| JP-H02119796-A | PRODUCTION OF L-HOMOPHENYLALANINE | BIO-LE KK | 1990-05-07 | — | — | JP | disclosed |
| JP-H01320991-A | PRODUCTION OF D-HOMOPHENYLALANINES | KANEGAFUCHI CHEM IND CO LTD | 1989-12-27 | — | — | JP | disclosed |
| JP-S6445336-A | PRODUCTION OF 2-(R)-HYDROXY-4-PHENYLLACTIC ACID DERIVATIVE | SAGAMI CHEM RES | 1989-02-17 | — | — | JP | disclosed |
| JP-S6445354-A | OPTICAL ACTIVE N-CARBAMOYL-2-(R)-AMINO-4-PHENYLBUTYRIC ACID | SAGAMI CHEM RES | 1989-02-17 | — | — | JP | disclosed |
| JP-S63273498-A | PRODUCTION OF L-2-AMINO-4-PHENYLBUTYRIC ACID | TANABE SEIYAKU CO LTD | 1988-11-10 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10421727-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPA1 | GAA 3493/4885ADAMTS5 3566/4885ADAMTS4 4001/4885 |
| US-11028052-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPA1 | GAA 3493/4885ADAMTS5 3566/4885ADAMTS4 4001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.