SCHEMBL6515702

SCHEMBL6515702

O=C(Nc1ccc(Oc2ccc(NC(=O)c3ccc(I)cc3)cc2)cc1)c1ccc(I)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 3/20 0.69
PGR P06401 2/20 0.67
RAB9A P51151 7/20 0.61
NPC1 O15118 5/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
TP53 P04637 1/20 0.61
ALOX15 P16050 1/20 0.61
HDAC1 Q13547 1/20 0.54
LMNA P02545 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
POLB P06746 1/20 0.52
PKM P14618 1/20 0.52
APEX1 P27695 1/20 0.52
HPGD P15428 1/20 0.52
TSHR P16473 1/20 0.52
HTT P42858 1/20 0.52
NR1H4 Q96RI1 1/20 0.51
KCNQ3 O43525 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3674376 0.89 TRPV1 (0.76) TRPV1RAB9ANPC1SMN1; SMN2TP53
SCHEMBL3679912 0.88 HPSE (0.64) TRPV1PGRRAB9ANPC1SMN1; SMN2
SCHEMBL1065119 0.86 RAB9A (0.83) TRPV1RAB9ANPC1SMN1; SMN2TP53
SCHEMBL22192258 0.84 PGR (0.93) PGRRAB9ANPC1SMN1; SMN2TP53
SCHEMBL22192259 0.84 PGR (0.74) PGRRAB9ANPC1SMN1; SMN2TP53
SCHEMBL20513016 0.84 PGR (0.74) PGRRAB9ANPC1SMN1; SMN2TP53
SCHEMBL22192221 0.82 POLB (0.79) PGRRAB9ANPC1SMN1; SMN2TP53
SCHEMBL809338 0.82 KMT2A (0.69) PGRRAB9ANPC1SMN1; SMN2TP53
SCHEMBL22192206 0.82 RAB9A (0.89) PGRRAB9ANPC1SMN1; SMN2TP53
SCHEMBL22694283 0.82 POLB (0.79) PGRRAB9ANPC1SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 US disclosed
EP-1245554-B1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORP (JP) 2005-01-26 EP disclosed
US-6812290-B2 FOR USE AS ELECTROLYTES JSR CORPORATION (JP) 2004-11-02 US disclosed
US-6794480-B2 POLYARYLENE-BASED COPOLYMER USEFUL AS PROTON-CONDUCTIVE MEMBRANE WHICH CAN BE USED AS ELECTRON FOR PRIMARY BATTERY, ELECTROLYTE FOR SECONDARY BATTERY, HIGH MOLECULAR SOLID ELECTROLYTE FOR FUEL CELL JSR CORPORATION (JP) 2004-09-21 US disclosed
US-20030195301-A1 Polyarylene copolymers and proton-conductive membrane JSR CORPORATION (JP) 2003-10-16 US disclosed
US-6555626-B2 Controlled amount of sulfonic acid groups; copolymer of an aromatic compound having a main chain containing electron withdrawing groups and aromatic compounds with no electron withdrawing groups; durability, strength, conductivity JSR CORPORATION (JP) 2003-04-29 US disclosed
US-20020177656-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORPORATION (JP) 2002-11-28 US disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed
EP-1245554-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR Corporation (JP) 2002-10-02 EP disclosed
US-20010037000-A1 Polyarylene copolymers and proton-conductive membrane JSR CORPORATION (JP) 2001-11-01 US disclosed
EP-1138712-A2 Polyarylene copolymers and proton-conductive membrane JSR Corporation (JP) 2001-10-04 EP disclosed