SCHEMBL809338

SCHEMBL809338

O=C(Nc1ccc(Oc2ccc(NC(=O)c3ccc(Cl)cc3)cc2)cc1)c1ccc(Cl)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.69
MEN1 O00255 3/20 0.69
PGR P06401 1/20 0.67
BRAF P15056 1/20 0.65
HDAC1 Q13547 1/20 0.65
ALDH1A1 P00352 3/20 0.65
HTT P42858 3/20 0.65
ALOX12 P18054 2/20 0.65
LMNA P02545 1/20 0.65
MAPT P10636 1/20 0.65
SMN1; SMN2 Q16637 4/20 0.63
NPSR1 Q6W5P4 2/20 0.63
PNLIP P16233 2/20 0.63
NPC1 O15118 4/20 0.63
RAB9A P51151 4/20 0.63
CYP2C9 P11712 1/20 0.62
CYP2C19 P33261 1/20 0.62
NT5E P21589 1/20 0.62
MAPK1 P28482 1/20 0.62
ENPP3 O14638 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17342684 0.92 ENPP1 (0.70) KMT2AMEN1PGRBRAFHDAC1
SCHEMBL9767723 0.89 NPC1 (0.76) KMT2AMEN1LMNAMAPTSMN1; SMN2
SCHEMBL611657 0.89 NPC1 (0.76) KMT2AMEN1LMNAMAPTSMN1; SMN2
SCHEMBL10939703 0.89 NPC1 (0.76) KMT2AMEN1LMNAMAPTSMN1; SMN2
SCHEMBL3673613 0.88 KMT2A (0.64) KMT2AMEN1PGRBRAFHDAC1
SCHEMBL11122035 0.86 NPC1 (0.83) KMT2AMEN1ALDH1A1SMN1; SMN2NPC1
SCHEMBL2121351 0.86 NPC1 (0.83) KMT2AMEN1ALDH1A1SMN1; SMN2NPC1
SCHEMBL22192258 0.84 PGR (0.93) KMT2AMEN1PGRHDAC1ALDH1A1
SCHEMBL22192259 0.84 PGR (0.74) KMT2AMEN1PGRHDAC1SMN1; SMN2
SCHEMBL20513016 0.84 PGR (0.74) KMT2AMEN1PGRHDAC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1693405-B1 PROTON CONDUCTING MEMBRANE AND PROCESS FOR PRODUCING THE SAME JSR CORP (JP) 2012-05-02 EP disclosed
EP-1845122-B1 POLYARYLENE, PROCESS FOR PRODUCING THE SAME, SOLID POLYELECTROLYTE, AND PROTON-CONDUCTIVE FILM JSR CORP (JP) 2011-11-16 EP disclosed
US-8058365-B2 Proton conducting membrane and process for producing the same JSR CORPORATION (JP) 2011-11-15 US disclosed
US-8039165-B2 Proton conductive membrane comprising a copolymer JSR CORPORATION (JP) 2011-10-18 US disclosed
US-7981566-B2 Membrane electrode assembly and polymer electrolyte fuel cell therewith HONDA MOTOR CO., LTD. (JP) 2011-07-19 US disclosed
US-7893303-B2 Polyarylene, process for producing the same, solid polyelectrolyte, and proton-conductive film JSR CORPORATION (JP) 2011-02-22 US disclosed
US-20100190088-A1 MEMBRANE ELECTRODE ASSEMBLY AND POLYMER ELECTROLYTE FUEL CELL THEREWITH HONDA MOTOR CO., LTD. (JP) 2010-07-29 US disclosed
US-7727652-B2 Membrane electrode assembly and polymer electrolyte fuel cell therewith HONDA MOTOR CO., LTD. (JP) 2010-06-01 US disclosed
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
EP-1482589-B1 Manufacturing process of membrane-electrode assemblies JSR CORP (JP) 2009-02-18 EP disclosed
US-20040043297-A1 Proton conductive resin composition, method for preparing the same, and proton conductive membrane comprising the composition JSR CORPORATION 2004-03-04 US disclosed
EP-1391480-A1 Proton conductive resin composition, method for preparing the same, and proton conductive membrane comprising the composition JSR Corporation (JP) 2004-02-25 EP disclosed
US-20040028806-A1 Process for producing electrolyte membrane-bonded electrode and varnish composition used therein THE RELIABLE AUTOMATIC SPRINKLER CO. INC. 2004-02-12 US disclosed
US-6685984-B2 FORMING FUEL CELL COMPRISED OF NONPENETRATING ELECTROLYTE MEMBRANE ON ELECTRODE JSR CORPORATION (JP) 2004-02-03 US disclosed
US-20030228421-A1 Method for the production of multilayers JSR CORPORATION 2003-12-11 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-20020177656-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORPORATION (JP) 2002-11-28 US disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed
EP-1245554-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR Corporation (JP) 2002-10-02 EP disclosed