Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 4/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27518334 | 0.85 | HSD11B1 (0.45) | MAOAHSD11B1CASP3CASP6BCHE | |
| SCHEMBL1254617 | 0.84 | HRH1 (0.41) | MAOAHRH1HSD11B1CYP2D6HTR2A | |
| Hydrochloric Acid SCHEMBL2276663 | 0.83 | HRH1 (0.40) | HRH1HSD11B1CYP2D6HTR2ACHRM2 | |
| SCHEMBL10929589 | 0.81 | TAAR1 (0.50) | CYP2D6 | |
| SCHEMBL10928781 | 0.80 | MAOA (0.36) | MAOAHRH1HSD11B1CYP2D6BCHE | |
| SCHEMBL20922751 | 0.80 | HRH1 (0.51) | HRH1HSD11B1CYP2D6HTR2ACHRM2 | |
| SCHEMBL27485969 | 0.79 | PNMT (0.39) | MAOAHSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL5027873 | 0.75 | MAOA (0.46) | MAOAHSD11B1TDP2CASP3CASP7 | |
| SCHEMBL29795069 | 0.75 | MAOA (0.46) | MAOAHSD11B1TDP2CASP3CASP7 | |
| SCHEMBL18230941 | 0.74 | ALDH1A1 (0.46) | MAOAHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872863-B2 | Methylene bridged metallocenes as olefin-polymerization catalyst components | BASELL POLYOLEFINE GMBH (DE) | 2005-03-29 | — | — | US | disclosed |
| US-20040147695-A1 | Methylene bridged metallocenes as olefin-polymerization catalyst components | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-07-29 | — | — | US | disclosed |
| US-6693156-B1 | SIMPLY AND EFFICIENTLY SYNTHESIZED MATERIALS WITH VARIED SUBSTITUTION FOR TAILORED POLYMER PROPERTIES | BASELL POLYOLEFINE GMBH (DE) | 2004-02-17 | — | — | US | disclosed |
| EP-1131328-B1 | METHYLENE BRIDGED METALLOCENES AS OLEFIN-POLYMERIZATION-CATALYST COMPONENTS | BASELL POLYOLEFINE GMBH (DE) | 2003-05-07 | — | — | EP | disclosed |
| US-6541584-B1 | Homo or copolymerizing one or more olefinic monomer in presence of a bis/tetrahydroindenyl/ metallocene catalyst | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-04-01 | — | — | US | disclosed |
| EP-1047702-B1 | BIS(TETRAHYYDRO-INDENYL) METALLOCENES AS OLEFIN-POLYMERIZATION- CATALYST | BASELL POLYOLEFINE GMBH (DE) | 2003-01-22 | — | — | EP | disclosed |
| EP-1131328-A1 | METHYLENE BRIDGED METALLOCENES AS OLEFIN-POLYMERIZATION-CATALYST COMPONENTS | Basell Technology Company B.V. (NL) | 2001-09-12 | — | — | EP | disclosed |
| EP-1047702-A1 | BIS(TETRAHYYDRO-INDENYL) METALLOCENES AS OLEFIN-POLYMERIZATION- CATALYST | Montell Technology Company bv (NL) | 2000-11-02 | — | — | EP | disclosed |
| WO-2000029415-A1 | METHYLENE BRIDGED METALLOCENES AS OLEFIN-POLYMERIZATION-CATALYST COMPONENTS | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2000-05-25 | — | — | WO | disclosed |
| WO-2000029416-A1 | BIS(TETRAHYDRO-INDENYL) METALLOCENES AS OLEFIN-POLYMERISATION-CATALYST | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 2000-05-25 | — | — | WO | disclosed |