Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3903162 | 0.91 | MAOB (0.48) | KMT2AMAOBDRD2HTR2AHTR2C | |
| SCHEMBL6510522 | 0.89 | KMT2A (0.41) | KMT2AMAOBDRD2HTR2AHTR2C | |
| SCHEMBL6513803 | 0.89 | DRD2 (0.38) | KMT2AMAOBDRD2HTR2AHTR2C | |
| SCHEMBL3895372 | 0.84 | KMT2A (0.48) | KMT2AMAOBDRD2HTR2AHTR2C | |
| SCHEMBL6509242 | 0.84 | MAOB (0.54) | KMT2AMAOBHTR2AHTR2CHTR6 | |
| Hydrochloric Acid SCHEMBL6504357 | 0.83 | MAOB (0.53) | KMT2AMAOBHTR2AHTR2CHTR6 | |
| SCHEMBL6517302 | 0.83 | DRD2 (0.42) | DRD2HTR2AHTR2CDRD3HTR6 | |
| SCHEMBL6509180 | 0.82 | DRD2 (0.41) | MAOBDRD2HTR2AHTR2CDRD3 | |
| SCHEMBL6509996 | 0.81 | HTR6 (0.39) | DRD2HTR2AHTR2CDRD3HTR6 | |
| SCHEMBL3893442 | 0.81 | HTR6 (0.49) | KMT2AMAOBDRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016891-A1 | 7-PHENYLSULFONYL-TETRAHYDRO-3-BENZAZEPINE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-24 | — | — | WO | claimed |
| WO-2005016891-A1 | 7-PHENYLSULFONYL-TETRAHYDRO-3-BENZAZEPINE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-24 | — | — | WO | disclosed |