Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6504357 | 0.99 | MAOB (0.53) | MAOBPKMMAPTLMNATSHR | |
| SCHEMBL3903162 | 0.93 | MAOB (0.48) | MAOBPKMHTR6MEN1KMT2A | |
| SCHEMBL6500880 | 0.90 | LMNA (0.51) | PKMMAPTLMNATSHRHTR6 | |
| SCHEMBL6502583 | 0.90 | LMNA (0.48) | PKMMAPTLMNATSHRHTR6 | |
| SCHEMBL6510748 | 0.90 | HTR6 (0.46) | MAOBPKMHTR6MEN1KMT2A | |
| SCHEMBL6504564 | 0.89 | HTR6 (0.54) | MAPTLMNATSHRHTR6HTR1A | |
| SCHEMBL6505255 | 0.88 | MAOB (0.45) | MAOBPKMMAPTLMNATSHR | |
| SCHEMBL6511504 | 0.88 | DRD2 (0.52) | MAPTLMNATSHRMEN1KMT2A | |
| SCHEMBL6502662 | 0.88 | HTR6 (0.45) | MAOBPKMMAPTLMNATSHR | |
| SCHEMBL6500345 | 0.88 | MAPT (0.51) | MAOBPKMMAPTLMNAHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | claimed |
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |