Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD5 | P21918 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517302 | 0.87 | DRD2 (0.42) | HTR6DRD1DRD4DRD5DRD2 | |
| SCHEMBL6517175 | 0.81 | KMT2A (0.43) | HTR6DRD1DRD4DRD5DRD2 | |
| SCHEMBL6513803 | 0.77 | DRD2 (0.38) | HTR6DRD1DRD4DRD5DRD2 | |
| SCHEMBL6509180 | 0.76 | DRD2 (0.41) | HTR6DRD1DRD4DRD5DRD2 | |
| SCHEMBL3903162 | 0.73 | MAOB (0.48) | HTR6DRD1DRD4DRD5DRD2 | |
| SCHEMBL3892485 | 0.73 | MAOA (0.47) | HTR6DRD1DRD4DRD5DRD2 | |
| SCHEMBL3907828 | 0.73 | MAOA (0.47) | HTR6DRD1DRD4DRD5DRD2 | |
| SCHEMBL3894400 | 0.73 | DRD1 (0.46) | HTR6DRD1DRD4DRD5DRD2 | |
| SCHEMBL6502583 | 0.73 | LMNA (0.48) | HTR6DRD1DRD4DRD5DRD2 | |
| SCHEMBL3906201 | 0.73 | DRD2 (0.44) | HTR6DRD1DRD4DRD5DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016891-A1 | 7-PHENYLSULFONYL-TETRAHYDRO-3-BENZAZEPINE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-24 | — | — | WO | claimed |
| WO-2005016891-A1 | 7-PHENYLSULFONYL-TETRAHYDRO-3-BENZAZEPINE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-24 | — | — | WO | disclosed |