Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517175 | 0.82 | KMT2A (0.43) | DRD2HTR2AHTR2CDRD3HTR6 | |
| SCHEMBL6517302 | 0.82 | DRD2 (0.42) | DRD2HTR2AHTR2CDRD3HTR6 | |
| SCHEMBL6513803 | 0.78 | DRD2 (0.38) | DRD2HTR2AHTR2CDRD3HTR6 | |
| SCHEMBL6509996 | 0.76 | HTR6 (0.39) | DRD2HTR2AHTR2CDRD3HTR6 | |
| SCHEMBL3907828 | 0.74 | MAOA (0.47) | DRD2HTR2AHTR2CDRD3HTR6 | |
| SCHEMBL3903162 | 0.74 | MAOB (0.48) | DRD2HTR2AHTR2CDRD3HTR6 | |
| SCHEMBL3892485 | 0.74 | MAOA (0.47) | DRD2HTR2AHTR2CDRD3HTR6 | |
| SCHEMBL3906201 | 0.74 | DRD2 (0.44) | DRD2HTR2AHTR2CDRD3HTR6 | |
| SCHEMBL6510522 | 0.74 | KMT2A (0.41) | DRD2HTR2AHTR2CDRD3HTR6 | |
| SCHEMBL6504564 | 0.73 | HTR6 (0.54) | DRD2HTR2AHTR2CDRD3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016891-A1 | 7-PHENYLSULFONYL-TETRAHYDRO-3-BENZAZEPINE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-24 | — | — | WO | claimed |
| WO-2005016891-A1 | 7-PHENYLSULFONYL-TETRAHYDRO-3-BENZAZEPINE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-24 | — | — | WO | disclosed |