Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 6/20 | 0.46 |
| ▸ | NOS1 | P29475 | 5/20 | 0.46 |
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | ARG1 | P05089 | 1/20 | 0.44 |
| ▸ | ARG2 | P78540 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 5/20 | 0.42 |
| ▸ | BHMT | Q93088 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | GGT1 | P19440 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14956142 | 1.00 | NOS2 (0.46) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL4954761 | 1.00 | NOS2 (0.46) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL195089 | 1.00 | NOS2 (0.46) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL8746612 | 0.98 | NOS2 (0.45) | NOS2NOS1NOS3ARG1ARG2 | |
| Hydrogen Sulfide SCHEMBL8495952 | 0.98 | NOS2 (0.45) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL1667369 | 0.84 | KIF11 (0.41) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL6835164 | 0.84 | KIF11 (0.41) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL3703131 | 0.84 | KIF11 (0.41) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL15932236 | 0.82 | ARG1 (0.48) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL2591190 | 0.82 | ARG1 (0.48) | NOS2NOS1NOS3ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104321338-A | Replacement therapy for dental caries | ORAGENICS INC | 2015-01-28 | — | — | CN | disclosed |
| CN-101939328-A | Genes and proteins for the biosynthesis of lantibiotics 107891 | SENTINELLA PHARMACEUTICALS INC | 2011-01-05 | — | — | CN | disclosed |
| WO-2005044977-A2 | COMPOSITIONS, SPLICE VARIANTS AND METHODS RELATING TO LUNG SPECIFIC GENES AND PROTEINS | DIADEXUS, INC. (US) | 2005-05-19 | — | — | WO | disclosed |