Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.41 |
| ▸ | NOS2 | P35228 | 6/20 | 0.40 |
| ▸ | NOS1 | P29475 | 5/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | GGT1 | P19440 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | BHMT | Q93088 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667369 | 1.00 | KIF11 (0.41) | KIF11NOS2NOS1NOS3ARG1 | |
| SCHEMBL3703131 | 1.00 | KIF11 (0.41) | KIF11NOS2NOS1NOS3ARG1 | |
| SCHEMBL14956142 | 0.84 | NOS2 (0.46) | KIF11NOS2NOS1NOS3ARG1 | |
| SCHEMBL6517552 | 0.84 | NOS2 (0.46) | KIF11NOS2NOS1NOS3ARG1 | |
| SCHEMBL4954761 | 0.84 | NOS2 (0.46) | KIF11NOS2NOS1NOS3ARG1 | |
| SCHEMBL195089 | 0.84 | NOS2 (0.46) | KIF11NOS2NOS1NOS3ARG1 | |
| SCHEMBL5517028 | 0.82 | NOS2 (0.48) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL5518580 | 0.82 | NOS2 (0.48) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL440968 | 0.82 | NOS2 (0.48) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL8746612 | 0.82 | NOS2 (0.45) | KIF11NOS2NOS1NOS3ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040018561-A1 | Peptide compounds and their use as protease substrates | PHARMACIA CORPORATION | 2004-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040018561-A1 | Peptide compounds and their use as protease substrates | MMP3, MMP25, MMP11 | KIF11 3124/4885NOS2 3024/4885NOS1 2502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.