Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28728908 | 0.98 | CES2 (0.52) | CES2CES1ALDH1A1POLBHPGD | |
| SCHEMBL2153551 | 0.87 | CES2 (0.62) | CES2CES1ALDH1A1POLBHPGD | |
| SCHEMBL8925810 | 0.86 | CES2 (0.52) | CES2CES1ALDH1A1POLBHPGD | |
| SCHEMBL30084385 | 0.85 | TSHR (0.52) | ALDH1A1POLBHPGDNPC1L3MBTL1 | |
| SCHEMBL2778 | 0.85 | TSHR (0.52) | ALDH1A1POLBHPGDNPC1L3MBTL1 | |
| SCHEMBL6383298 | 0.83 | TSHR (0.50) | ALDH1A1POLBHPGDNPC1L3MBTL1 | |
| Acetone SCHEMBL29281281 | 0.83 | TSHR (0.50) | ALDH1A1POLBHPGDNPC1L3MBTL1 | |
| SCHEMBL1896602 | 0.83 | TSHR (0.50) | ALDH1A1POLBHPGDNPC1L3MBTL1 | |
| SCHEMBL27931437 | 0.83 | TSHR (0.50) | ALDH1A1POLBHPGDNPC1L3MBTL1 | |
| SCHEMBL28206063 | 0.83 | TSHR (0.50) | ALDH1A1POLBHPGDNPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606923-B | Synthesis method of racemic clopidogrel | 武汉理工大学 | 2021-08-24 | — | — | CN | claimed |
| CN-111606923-A | Synthesis method of racemic clopidogrel | 武汉理工大学 | 2020-09-01 | — | — | CN | claimed |
| CN-118308316-A | Biocatalysis asymmetric reaction reductase and application thereof | 湖州师范学院 | 2024-07-09 | — | — | CN | disclosed |
| CN-118308316-A | Biocatalysis asymmetric reaction reductase and application thereof | 湖州师范学院 | 2024-07-09 | — | — | CN | disclosed |
| CN-114605241-B | Preparation method of esketamine hydrochloride intermediate and intermediate thereof | 宜昌人福药业有限责任公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-110272879-B | Aldehyde ketone reductase BcAKR and mutant and application thereof | 沈阳药科大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-110272879-B | Aldehyde ketone reductase BcAKR and mutant and application thereof | 沈阳药科大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-111484986-B | Short-chain dehydrogenase and application thereof | 沈阳药科大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-114605241-A | Preparation method of esketamine hydrochloride intermediate and intermediate thereof | 宜昌人福药业有限责任公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114478241-A | Preparation method of arylformyl formic ether | 山东京博生物科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-111606923-B | Synthesis method of racemic clopidogrel | 武汉理工大学 | 2021-08-24 | — | — | CN | disclosed |
| CN-111393291-A | Novel synthesis method of α -carbonyl acid ester | 宁波海曙琼杰化工技术研发工作室 | 2020-07-10 | — | — | CN | disclosed |
| CN-107548396-B | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-110272879-A | Aldehyde ketone reductase BcAKR and its mutant and application | 沈阳药科大学 | 2019-09-24 | — | — | CN | disclosed |
| CN-110272879-A | Aldehyde ketone reductase BcAKR and its mutant and application | 沈阳药科大学 | 2019-09-24 | — | — | CN | disclosed |
| CN-108929226-A | A method of preparing benzoyl formic acid ester derivant | 广东工业大学 | 2018-12-04 | — | — | CN | disclosed |
| CN-103820521-B | Living things catalysis Dynamic Kinetic Resolution prepares the method for R-o-chloromandelic acid methyl ester | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |
| CN-1976892-A | Substituted enaminones, their derivatives and their use | UNIV CALIFORNIA (US) | 2007-06-06 | — | — | CN | disclosed |
| US-20050153404-A1 | Anti-kazlauskas lipases | LANXESS DEUTSCHLAND GMBH (DE) | 2005-07-14 | — | — | US | disclosed |
| CN-86107627-A | The preparation method of novel 4-benzyl-1-(2H)-phthalazinone derivatives | — | 1987-07-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153404-A1 | Anti-kazlauskas lipases | CEL, LIPA, LPL | CES2 22/4885CES1 13/4885ALDH1A1 735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.