SCHEMBL8925810

SCHEMBL8925810

C=C(C)OC(=O)c1ccccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
ALDH1A1 P00352 2/20 0.50
POLB P06746 2/20 0.47
HPGD P15428 2/20 0.46
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.46
GAA P10253 1/20 0.46
PKM P14618 1/20 0.46
NFKB1 P19838 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KMT2A Q03164 2/20 0.45
USP2 O75604 1/20 0.44
TSHR P16473 2/20 0.44
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
CYP1A2 P05177 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6518565 0.86 CES2 (0.54) CES2CES1ALDH1A1POLBHPGD
SCHEMBL2153551 0.86 CES2 (0.62) CES2CES1ALDH1A1POLBHPGD
SCHEMBL11765420 0.86 TSHR (0.50) ALDH1A1POLBHPGDNPC1L3MBTL1
SCHEMBL28728908 0.85 CES2 (0.52) CES2CES1ALDH1A1POLBHPGD
SCHEMBL6206781 0.80 RAB9A (0.50) CES2CES1ALDH1A1POLBHPGD
SCHEMBL3755789 0.79 CES2 (0.50) CES2CES1ALDH1A1POLBHPGD
SCHEMBL10491973 0.79 ALDH1A1 (0.53) CES2CES1ALDH1A1POLBHPGD
SCHEMBL10905341 0.79 TSHR (0.52) CES2CES1ALDH1A1POLBHPGD
SCHEMBL29262199 0.79 ADRB2 (0.46) CES2CES1ALDH1A1POLBHPGD
SCHEMBL29220302 0.78 ALDH1A1 (0.56) ALDH1A1HPGDSMN1; SMN2TSHRESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5627240-A PAINT BINDER, N-ACRYLOYLCARBAMATE POLYMER, LACTONE-MODIFIED LOWER POLYHYDRIC ALCOHOL NIPPON PAINT CO., LTD. (JP) 1997-05-06 US disclosed
EP-0243160-B2 Blocked isocyanatocarbonyl group-containing polymers NIPPON PAINT CO LTD (JP) 1996-11-13 EP disclosed
EP-0207621-B1 Functional polymers and their production NIPPON PAINT CO LTD (JP) 1995-04-05 EP disclosed
EP-0630921-A2 Functional polymers and their production NIPPON PAINT CO., LTD. (JP) 1994-12-28 EP disclosed
US-5274062-A An N-(substituted oxalyl)-halopropionamide NIPPON PAINT CO., LTD. (JP) 1993-12-28 US disclosed
US-5208308-A N-Oxalyl-Substituted NIPPON PAINT CO., LTD. (JP) 1993-05-04 US disclosed
EP-0206544-B1 INSTANTANEOUSLY CURABLE COMPOSITION Nippon Paint Co., Ltd. (JP) 1992-01-08 EP disclosed
US-4970281-A COATINGS, ADHESIVES, MOLDING NIPPON PAINT CO., LTD. (JP) 1990-11-13 US disclosed
US-4956491-A MONOMERS FOR RESINS USED IN COATINGS, ADHESIVES OR MOLDING MATERIALS NIPPON PAINT CO., LTD. (JP) 1990-09-11 US disclosed
US-4914225-A MOLDING MATERIALS, COATINGS, ADHESIVES NIPPON PAINT CO., LTD. (JP) 1990-04-03 US disclosed
US-4035275-A ELECTRODEPOSITION, CATIONIC EPOXY RESINS PPG INDUSTRIES, INC. (US) 1977-07-12 US disclosed
US-4031290-A ALPHA-BETA MONOMERS, CATALYSIS PPG INDUSTRIES, INC. (US) 1977-06-21 US disclosed
US-4016332-A OF ETHYLENICALLY UNSATURATED MONOMERS PPG INDUSTRIES, INC. (US) 1977-04-05 US disclosed
US-4001156-A Method of producing epoxy group-containing, quaternary ammonium salt-containing resins PPG INDUSTRIES, INC. (US) 1977-01-04 US disclosed
US-3975346-A ELECTRO-DEPOSITION PPG INDUSTRIES, INC. (US) 1976-08-17 US disclosed
US-3959106-A EPOXY COMPOUNDS; SULFIDES PPG INDUSTRIES, INC. (US) 1976-05-25 US disclosed
US-3939051-A Process for electrodeposition of cationic thermosetting compositions PPG INDUSTRIES, INC. (US) 1976-02-17 US disclosed
US-3937679-A COATINGS, AMMONIUM, SULFONIUM, OR PHOSPHONIUM ACID SALT, AMINE-ALDEHYDE CONDENSATE, AND A METHYOL PHENOL ETHER PPG INDUSTRIES, INC. (US) 1976-02-10 US disclosed
US-3936405-A CATIONIC POLYMER PPG INDUSTRIES, INC. (US) 1976-02-03 US disclosed
US-3933940-A Mercaptan blocked thermosetting copolymers PPG INDUSTRIES, INC. (US) 1976-01-20 US disclosed