SCHEMBL6518873

SCHEMBL6518873

C=C(C(=O)O)C(CC(=O)Oc1ccc(C)cc1)(C(=O)O)c1ccc(C)cc1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.40
GAA P10253 2/20 0.40
KMT2A Q03164 3/20 0.39
ALDH1A1 P00352 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
NPC1 O15118 1/20 0.36
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HSP90AA1 P07900 1/20 0.33
MMP13 P45452 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6523105 0.95 ALDH1A1 (0.40) LMNAGAAKMT2AALDH1A1L3MBTL1
SCHEMBL6520850 0.95 ALDH1A1 (0.38) LMNAGAAKMT2AALDH1A1L3MBTL1
SCHEMBL6524368 0.86 NPC1 (0.36) LMNAGAAKMT2AALDH1A1TDP1
SCHEMBL6517368 0.85 CYP19A1 (0.38) KMT2AALDH1A1L3MBTL1TDP1MAPT
SCHEMBL6513735 0.83 LMNA (0.44) LMNAGAAKMT2AALDH1A1L3MBTL1
SCHEMBL6518805 0.81 NPC1 (0.35) LMNAGAAKMT2AALDH1A1TDP1
SCHEMBL6524253 0.81 TDP1 (0.39) LMNAGAAKMT2AALDH1A1L3MBTL1
SCHEMBL6516686 0.80 L3MBTL1 (0.40) LMNAGAAKMT2AALDH1A1L3MBTL1
SCHEMBL6514385 0.80 LMNA (0.45) LMNAKMT2AALDH1A1L3MBTL1TDP1
SCHEMBL6515893 0.79 NPC1 (0.46) LMNAGAAKMT2AALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958366-B2 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-25 US disclosed