SCHEMBL6520850

SCHEMBL6520850

C=C(C(=O)O)C(CC(=O)Oc1ccccc1)(C(=O)O)c1ccc(C)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.36
GAA P10253 2/20 0.36
USP2 O75604 1/20 0.36
KMT2A Q03164 1/20 0.35
MAPK14 Q16539 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MAPT P10636 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CYP19A1 P11511 1/20 0.34
ELANE P08246 1/20 0.34
PTK2B Q14289 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
KIF11 P52732 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6523105 0.95 ALDH1A1 (0.40) ALDH1A1LMNAGAAKMT2ANPSR1
SCHEMBL6518873 0.95 LMNA (0.40) ALDH1A1LMNAGAAKMT2AMAPT
SCHEMBL6517368 0.91 CYP19A1 (0.38) ALDH1A1KMT2AMAPTTDP1L3MBTL1
SCHEMBL6524368 0.84 NPC1 (0.36) ALDH1A1LMNAGAAKMT2AMAPT
SCHEMBL6514385 0.82 LMNA (0.45) ALDH1A1LMNAKMT2AMAPTTDP1
SCHEMBL6518104 0.81 GPR139 (0.38) ALDH1A1USP2KMT2ANPSR1MAPT
SCHEMBL6518190 0.81 L3MBTL1 (0.47) LMNAGAAKMT2AMAPTTDP1
SCHEMBL6516686 0.80 L3MBTL1 (0.40) ALDH1A1LMNAGAAKMT2AMAPT
SCHEMBL6519557 0.80 KMT2A (0.47) ALDH1A1LMNAKMT2ANPSR1MAPT
SCHEMBL6518805 0.79 NPC1 (0.35) ALDH1A1LMNAGAAKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958366-B2 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-25 US disclosed
US-20030118544-A1 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118544-A1 Antifouling coating composition and novel resin COL1A1, GLRA1, COL2A1 ALDH1A1 1254/4885LMNA 2459/4885GAA 3231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.