SCHEMBL6524368

SCHEMBL6524368

C=C(C(=O)O)C(CC(=O)OC)(C(=O)O)c1ccc(C)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
MAPT P10636 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
VEGFA P15692 1/20 0.34
FLT1 P17948 1/20 0.34
EGLN1 Q9GZT9 1/20 0.34
EGLN3 Q9H6Z9 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 2/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 3/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6515804 0.88 KCNN4 (0.41) MEN1KMT2APOLBLMNAALDH1A1
SCHEMBL6518873 0.86 LMNA (0.40) NPC1MAPTTDP1MEN1KMT2A
SCHEMBL6524253 0.85 TDP1 (0.39) NPC1RAB9ATDP1MEN1KMT2A
SCHEMBL6520850 0.84 ALDH1A1 (0.38) MAPTTDP1KMT2ALMNAALDH1A1
SCHEMBL6518805 0.84 NPC1 (0.35) NPC1RAB9AMAPTTDP1MEN1
SCHEMBL6514385 0.82 LMNA (0.45) NPC1RAB9AMAPTTDP1KMT2A
SCHEMBL6523105 0.81 ALDH1A1 (0.40) NPC1MAPTTDP1MEN1KMT2A
SCHEMBL6515893 0.81 NPC1 (0.46) NPC1RAB9AMAPTMEN1KMT2A
SCHEMBL6519436 0.81 CYP19A1 (0.36) NPC1RAB9AMAPTMEN1KMT2A
SCHEMBL6518104 0.80 GPR139 (0.38) MAPTMEN1KMT2AALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958366-B2 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-25 US disclosed
US-20030118544-A1 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118544-A1 Antifouling coating composition and novel resin COL1A1, GLRA1, COL2A1 NPC1 3563/4885RAB9A 2333/4885MAPT 3438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.