SCHEMBL6519850

SCHEMBL6519850

Cc1ccc2c(c1)SC(c1ccc(N(C)C)cc1)N2C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDGFRB P09619 1/20 0.42
▸ ALDH1A1 P00352 5/20 0.39
▸ TSHR P16473 1/20 0.39
▸ HTR7 P34969 2/20 0.37
▸ INSR P06213 2/20 0.35
▸ APP P05067 5/20 0.33
▸ SNCA P37840 3/20 0.33
▸ TNF P01375 1/20 0.33
▸ NOD1 Q9Y239 1/20 0.33
▸ MEN1 O00255 4/20 0.32
▸ KMT2A Q03164 4/20 0.32
▸ KDM4E B2RXH2 3/20 0.32
▸ MAPT P10636 3/20 0.32
▸ CASP1 P29466 2/20 0.32
▸ CASP7 P55210 2/20 0.32
▸ HTT P42858 1/20 0.32
▸ NPC1 O15118 2/20 0.32
▸ RAB9A P51151 2/20 0.32
▸ GAA P10253 2/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28295077 0.99 PDGFRB (0.41) PDGFRBALDH1A1TSHRHTR7INSR
Hydrochloric Acid SCHEMBL28166077 0.99 PDGFRB (0.41) PDGFRBALDH1A1TSHRHTR7INSR
SCHEMBL28924615 0.77 PDGFRB (0.36) PDGFRBALDH1A1TSHRHTR7MEN1
SCHEMBL30160329 0.77 PDGFRB (0.36) PDGFRBALDH1A1TSHRHTR7MEN1
SCHEMBL21970993 0.72 PDGFRB (0.43) PDGFRBALDH1A1TSHRHTR7SNCA
SCHEMBL30542467 0.70 NPSR1 (0.34) KMT2A
SCHEMBL11515562 0.70 NPSR1 (0.34) KMT2A
SCHEMBL11516459 0.69 SNCA (0.44) PDGFRBALDH1A1TSHRHTR7APP
SCHEMBL9307101 0.68 AADAT (0.34) SMN1; SMN2TDP1TP53
SCHEMBL4625857 0.68 ALOX5 (0.41) ALDH1A1HTR7ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109266784-B Closed DNA fluorescent biosensor and application thereof in detection of influenza A H1N1 virus 广东海洋大学 2022-04-08 — — CN claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 — — EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 — — EP claimed
CN-115517262-B Application of thioflavin T in resisting plant virus 中国科学院武汉植物园 2023-11-07 — — CN disclosed
CN-115517262-B Application of thioflavin T in resisting plant virus 中国科学院武汉植物园 2023-11-07 — — CN disclosed
CN-109266783-B Molecular beacon-G quadruplex optical sensor and application thereof in detection of SV40 virus 广东海洋大学 2022-07-22 — — CN disclosed
CN-109266784-B Closed DNA fluorescent biosensor and application thereof in detection of influenza A H1N1 virus 广东海洋大学 2022-04-08 — — CN disclosed
US-20050282733-A1 Differentiation modulating agents and uses therefor VERVA PHARMACEUTICALS PTY LTD (AU) 2005-12-22 — — US disclosed
CN-1173954-C Compounds, compositions and methods for generating chemiluminescence by reaction with phosphatases 3 2004-11-03 — — CN disclosed
CN-1312252-A Intermediate of chemical compound generating chemical illumination when reacts with phosphatase RUMIGEN CO (US) 2001-09-12 — — CN disclosed
CN-1180349-A Compounds, compositions and methods for generating chemiluminescence by reaction with phosphatases LUMIGEN INC (US) 1998-04-29 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050282733-A1 Differentiation modulating agents and uses therefor FGF1, FABP4, FGF2 PDGFRB 467/4885ALDH1A1 1103/4885TSHR 2056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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