Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7161047 | 0.83 | PARP1 (0.44) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL8813905 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL967996 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL7466281 | 0.80 | MMP2 (0.45) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL12635358 | 0.80 | KDM4E (0.61) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL31493861 | 0.80 | KDM4E (0.61) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL2685882 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL11768320 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL608549 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL3069325 | 0.79 | MAPT (0.38) | ALDH1A1KDM4EMAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279887-A | RADIOACTIVE SCANNING | MEDI-PHYSICS, INC. (US) | 1981-07-21 | — | — | US | claimed |
| CN-122094719-A | System with improved hydrogel formation time | — | 2026-05-26 | — | — | CN | disclosed |
| US-20250128220-A1 | SYSTEMS WITH IMPROVED HYDROGEL FORMATION TIMES | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2025-04-24 | — | — | US | disclosed |
| WO-2025085642-A1 | SYSTEMS WITH IMPROVED HYDROGEL FORMATION TIMES | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| US-9662059-B2 | Imaging agents for monitoring changes of dopamine receptors and methods of using thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-05-30 | — | — | US | disclosed |
| EP-2013196-B1 | DISUBSTITUTED ANILINE COMPOUNDS | MERCK SHARP & DOHME (US) | 2015-09-16 | — | — | EP | disclosed |
| US-8877943-B2 | Radiotracer precursor and method for preparing the same | Atomic Energy Council-Institute of Nuclear Eenergy Research (TW) | 2014-11-04 | — | — | US | disclosed |
| US-20140073803-A1 | RADIOTRACER PRECURSOR AND METHOD FOR PREPARING THE SAME | ATOMIC ENERGY COUNCIL - INSTITUTE OF NUCLEAR ENERGY RESEARCH (TW) | 2014-03-13 | — | — | US | disclosed |
| US-8119685-B2 | Disubstituted aniline compounds | MERCK SHARP & DOHME CORP. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20090221669-A1 | Disubstituted Aniline Compounds | MERCK SHARP & DOHME LLC | 2009-09-03 | — | — | US | disclosed |
| US-20070004695-A1 | THIENOISOXAZOLYL-AND THIENYLPYRRAZOLYL PHENOXY SUBSTITUTED PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | US | disclosed |
| US-7125903-B1 | Thienoisoxazolyl-and thienylpyrrazolyl-phenoxy substituted propyl derivatives useful as D4 antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2006-10-24 | — | — | US | disclosed |
| US-7091199-B1 | Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2006-08-15 | — | — | US | disclosed |
| US-20050107377-A1 | Benzisoxazolyl-,pyridoisoxazolyl-and benzthienyl-phenoxy derivatives useful as D4 antagonists | AVENTIS PHARMACEUTIALS INC. (US) | 2005-05-19 | — | — | US | disclosed |
| WO-2005000250-A2 | IMAGING AGENTS AND METHODS OF IMAGING ALPHA 7-NICOTINIC CHOLINERGIC RECEPTOR | JOHNS HOPKINS UNIVERSITY (US) | 2005-01-06 | — | — | WO | disclosed |
| EP-1216249-B1 | THIENOISOXAZOLE PHENOXY UNSUBSTITUTED ETHYL AND PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMA INC (US) | 2003-11-19 | — | — | EP | disclosed |
| EP-1216250-B1 | THIENOISOXAZOLYL AND THIENYLPYRRAZOLYL PHENOXY SUBSTITUTED PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMA INC (US) | 2003-11-19 | — | — | EP | disclosed |
| EP-1216244-B1 | Benzisoxazolyl-, pyridoisoxazolyl- and benzthienyl-phenoxy derivatives useful as D4 antagonists | AVENTIS PHARMA INC (US) | 2003-08-13 | — | — | EP | disclosed |
| EP-0617892-A1 | A veterinary medicament for preventive treatment and therapy of cattle against parasites | HAK PHARMA B.V. (NL) | 1994-10-05 | — | — | EP | disclosed |
| US-4279887-A | RADIOACTIVE SCANNING | MEDI-PHYSICS, INC. (US) | 1981-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107377-A1 | Benzisoxazolyl-,pyridoisoxazolyl-and benzthienyl-phenoxy derivatives useful as D4 antagonists | DRD4, DRD2, DRD1 | ALDH1A1 895/4885KDM4E 710/4885MAPT 347/4885 |
| US-20070004695-A1 | THIENOISOXAZOLYL-AND THIENYLPYRRAZOLYL PHENOXY SUBSTITUTED PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | DRD4, DRD2, SLC6A3 | ALDH1A1 961/4885KDM4E 986/4885MAPT 391/4885 |
| US-20090221669-A1 | Disubstituted Aniline Compounds | TXNRD2, BRDT, HDAC1 | ALDH1A1 744/4885KDM4E 500/4885MAPT 819/4885 |
| US-20140073803-A1 | RADIOTRACER PRECURSOR AND METHOD FOR PREPARING THE SAME | SLC6A3, DBH, BRS3 | ALDH1A1 3265/4885KDM4E 4571/4885MAPT 1088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.