Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 4/20 | 0.40 |
| ▸ | IKBKB | O14920 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19972002 | 0.81 | MMP2 (0.44) | MMP2ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL652047 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL31493861 | 0.78 | KDM4E (0.61) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL12635358 | 0.78 | KDM4E (0.61) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL998313 | 0.77 | MMP2 (0.48) | MMP2ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL21296300 | 0.77 | METAP2 (0.50) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL30213820 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL18297631 | 0.77 | CES2 (0.47) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL4523553 | 0.77 | MYC (0.48) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL28415609 | 0.77 | KDM4E (0.43) | ALDH1A1KDM4EMAPTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877185-A | THERAPY FOR CANCER OR RETROVIRUS | OCTAMER, INC. (US) | 1999-03-02 | — | — | US | disclosed |
| WO-1996022791-A9 | NOVEL SYNERGISTIC COMPOSITIONS USEFUL AS ANTI-TUMOR OR ANTI-RETROVIRAL AGENTS | — | 1996-10-03 | — | — | WO | disclosed |
| WO-1996022791-A1 | NOVEL SYNERGISTIC COMPOSITIONS USEFUL AS ANTI-TUMOR OR ANTI-RETROVIRAL AGENTS | OCTAMER, INC. (US) | 1996-08-01 | — | — | WO | disclosed |