Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.68 |
| ▸ | AKR1B10 | O60218 | 5/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.51 |
| ▸ | TTR | P02766 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860306 | 0.86 | HCAR2 (0.89) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| SCHEMBL3482701 | 0.86 | HCAR2 (0.89) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| SCHEMBL573377 | 0.86 | HCAR2 (0.89) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| SCHEMBL6523784 | 0.85 | HCAR2 (0.66) | HCAR2AKR1B10AKR1B1MAOBTTR | |
| SCHEMBL27735855 | 0.84 | HCAR2 (0.76) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| SCHEMBL25623741 | 0.81 | HCAR2 (0.76) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| Phenylethyl Fumarate SCHEMBL573376 | 0.81 | HCAR2 (1.00) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| Phenylethyl Fumarate SCHEMBL573379 | 0.81 | HCAR2 (1.00) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| Phenylethyl Fumarate SCHEMBL27750209 | 0.81 | HCAR2 (1.00) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| SCHEMBL1845413 | 0.80 | HCAR2 (0.73) | HCAR2AKR1B10AKR1B1MAOBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958366-B2 | Antifouling coating composition and novel resin | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-10-25 | — | — | US | disclosed |
| US-20030118544-A1 | Antifouling coating composition and novel resin | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030118544-A1 | Antifouling coating composition and novel resin | COL1A1, GLRA1, COL2A1 | HCAR2 3143/4885AKR1B10 2430/4885AKR1B1 2731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.