Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.38 |
| ▸ | TK1 | P04183 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | DUT | P33316 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537871 | 0.87 | HDAC1 (0.42) | HDAC1HDAC2HDAC8HDAC6YTHDC1 | |
| SCHEMBL14334376 | 0.86 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8539832 | 0.85 | TK1 (0.46) | HDAC1HDAC2HDAC8HDAC6YTHDC1 | |
| SCHEMBL14331795 | 0.83 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL14334463 | 0.82 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL30114962 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL3155583 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8538543 | 0.77 | HDAC1 (0.52) | HDAC1HDAC2HDAC8HDAC6YTHDC1 | |
| SCHEMBL8539778 | 0.75 | CDK1 (0.49) | — | |
| SCHEMBL28434898 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556383-A1 | PROCESS FOR PREPARING FAMCICLOVIR | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2005-07-27 | — | — | EP | disclosed |
| WO-2005026167-A1 | PROCESS FOR PREPARING FAMCICLOVIR | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2005-03-24 | — | — | WO | disclosed |