Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 6/20 | 0.49 |
| ▸ | PRKCA | P17252 | 2/20 | 0.49 |
| ▸ | IDH2 | P48735 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537871 | 0.86 | HDAC1 (0.42) | LMNAMAPK1 | |
| SCHEMBL8535480 | 0.82 | TK1 (0.52) | — | |
| SCHEMBL8539832 | 0.80 | TK1 (0.46) | — | |
| SCHEMBL5801330 | 0.75 | HDAC3 (0.40) | — | |
| SCHEMBL6523725 | 0.75 | KDM4E (0.48) | — | |
| SCHEMBL12537333 | 0.73 | P2RX7 (0.50) | LMNAMAPT | |
| SCHEMBL8536493 | 0.69 | TK1 (0.45) | — | |
| SCHEMBL8157896 | 0.69 | CTSL (0.51) | — | |
| SCHEMBL20973093 | 0.68 | MAPT (0.42) | LMNAMAPTNR3C1 | |
| SCHEMBL5839910 | 0.68 | CDK1 (0.69) | CDK1PRKCAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794781-A4 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIV MASSACHUSETTS MEDICAL (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0794781-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-09-17 | — | — | EP | disclosed |
| US-5646155-A | ADMINISTERING A 9-SUBSTITUTED-N2-PHENYLGUANINE DERIVATIVE | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-07-08 | — | — | US | disclosed |
| WO-1996020711-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-07-11 | — | — | WO | disclosed |