Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 10/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440415 | 0.88 | PSEN1 (0.48) | NOD1HTR6PSEN1PSEN2APH1B | |
| SCHEMBL6435967 | 0.86 | HTR6 (0.54) | NOD1HTR6PSEN1PSEN2APH1B | |
| SCHEMBL6526507 | 0.86 | LMNA (0.47) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3561274 | 0.84 | HTR6 (0.45) | NOD1HTR6CYP3A4CYP2D6PCSK9 | |
| SCHEMBL6440512 | 0.76 | PTGDR2 (0.48) | NOD1HTR6PSEN1PSEN2APH1B | |
| SCHEMBL6442219 | 0.76 | PTGDR2 (0.43) | NOD1HTR6PSEN1PSEN2APH1B | |
| SCHEMBL6440106 | 0.74 | LMNA (0.51) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6442471 | 0.74 | PSEN1 (0.43) | NOD1HTR6PSEN1PSEN2APH1B | |
| SCHEMBL6439680 | 0.74 | HTR6 (0.41) | HTR6LMNA | |
| SCHEMBL6436468 | 0.73 | PTGDR (0.45) | NOD1HTR6PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567492-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | Suven Life Sciences Limited (IN) | 2005-08-31 | — | — | EP | claimed |
| WO-2004048328-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |