Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 4/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.71 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.70 |
| ▸ | TRPA1 | O75762 | 7/20 | 0.68 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.58 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.58 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6525729 | 1.00 | TRPM2 (0.76) | TRPM2KMT2ACYP3A4CYP2C9LTB4R | |
| SCHEMBL6097501 | 0.88 | KMT2A (0.72) | TRPM2KMT2ACYP3A4CYP2C9LTB4R | |
| SCHEMBL6791025 | 0.86 | ALDH1A1 (0.80) | TRPM2KMT2ALTB4RMEN1MAPT | |
| SCHEMBL6791019 | 0.86 | ALDH1A1 (0.80) | TRPM2KMT2ALTB4RMEN1MAPT | |
| SCHEMBL2273179 | 0.86 | TRPM2 (0.77) | TRPM2KMT2ACYP3A4CYP2C9LTB4R | |
| SCHEMBL2273176 | 0.86 | TRPM2 (0.77) | TRPM2KMT2ACYP3A4CYP2C9LTB4R | |
| SCHEMBL294403 | 0.85 | TRPM2 (0.83) | TRPM2KMT2ACYP3A4CYP2C9LTB4R | |
| SCHEMBL294402 | 0.85 | TRPM2 (0.83) | TRPM2KMT2ACYP3A4CYP2C9LTB4R | |
| SCHEMBL29401064 | 0.84 | TRPM2 (0.81) | TRPM2KMT2ACYP3A4CYP2C9LTB4R | |
| SCHEMBL2778920 | 0.84 | TRPM2 (0.81) | TRPM2KMT2ACYP3A4CYP2C9LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110054034-A1 | METHODS OF USING CARBOXYLIC AMIDES AS ANTIMICROBIAL AGENTS | GRAND VALLEY STATE UNIVERSITY | 2011-03-03 | — | — | US | claimed |
| US-20110054034-A1 | METHODS OF USING CARBOXYLIC AMIDES AS ANTIMICROBIAL AGENTS | GRAND VALLEY STATE UNIVERSITY | 2011-03-03 | — | — | US | disclosed |
| US-6127392-A | A MUSCLE RELAXANT FOR TREATMENT OF DISORDERS ASSOCIATED WITH SMOOTH MUSCLE CONTRACTION VIA POTASSIUM CHANNEL AND CHLORIDE CHANNEL MODULATION; INOTROPIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054034-A1 | METHODS OF USING CARBOXYLIC AMIDES AS ANTIMICROBIAL AGENTS | NAAA, ELANE, APEH | TRPM2 2644/4885KMT2A 1670/4885CYP3A4 3614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.