Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526403 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1NPC1LMNAMAPTRAB9A | |
| SCHEMBL6525786 | 0.75 | TDP1 (0.43) | ALDH1A1NPC1LMNAMAPTRAB9A | |
| SCHEMBL1536850 | 0.74 | LMNA (0.48) | ALDH1A1NPC1LMNAMAPTRAB9A | |
| SCHEMBL6528307 | 0.74 | ALDH1A1 (0.48) | ALDH1A1NPC1LMNAMAPTRAB9A | |
| SCHEMBL10843980 | 0.71 | HRH4 (0.38) | ALDH1A1LMNAGAAKMT2AHRH4 | |
| SCHEMBL9866407 | 0.71 | NPSR1 (0.58) | ALDH1A1LMNAMAPTKDM4EGAA | |
| SCHEMBL6525905 | 0.71 | ALDH1A1 (0.44) | ALDH1A1NPC1LMNAMAPTRAB9A | |
| SCHEMBL10852555 | 0.71 | RAB9A (0.47) | NPC1LMNAMAPTRAB9AHPGD | |
| SCHEMBL5104251 | 0.69 | AAK1 (0.44) | RAB9AKDM4EGAAHRH4HTR3A | |
| SCHEMBL1171146 | 0.68 | ALDH1A1 (0.53) | ALDH1A1NPC1MAPTRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575925-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056784-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-08 | — | — | WO | disclosed |