Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5845501 | 0.83 | SIGMAR1 (0.56) | POLBMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL16054115 | 0.81 | CYP1A2 (0.43) | POLBMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL6529829 | 0.80 | POLB (0.45) | POLBMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL3723081 | 0.79 | SIGMAR1 (0.64) | POLBMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL738862 | 0.79 | SIGMAR1 (0.47) | POLBSIGMAR1 | |
| SCHEMBL3718831 | 0.78 | SIGMAR1 (0.60) | POLBMEN1KMT2ASIGMAR1 | |
| SCHEMBL23064564 | 0.77 | MEN1 (0.43) | POLBMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL28795437 | 0.74 | CTSB (0.48) | POLBMEN1KMT2ALMNAKDM4E | |
| SCHEMBL28344098 | 0.74 | SIGMAR1 (0.49) | POLBMEN1KMT2ASIGMAR1MAPT | |
| SCHEMBL16054145 | 0.73 | MAPT (0.51) | MEN1KMT2ACYP1A2CYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005021547-A2 | HETEROCYCLIC CANNABINOID CB2 RECEPTOR ANTAGONISTS | PHARMAXIS PTY LTD. (AU) | 2005-03-10 | — | — | WO | disclosed |